Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 12/20 | 0.50 |
| ▸ | F2 | P00734 | 4/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 8/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 8/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16189986 | 0.80 | F10 (0.51) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL16730530 | 0.79 | F10 (0.59) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL5477668 | 0.78 | F10 (0.66) | F10F2SLC29A1 | |
| SCHEMBL6218254 | 0.76 | F10 (0.69) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL5482613 | 0.76 | F10 (0.57) | F10F2SLC29A1 | |
| SCHEMBL19975899 | 0.75 | F10 (0.67) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL16189955 | 0.74 | F10 (0.52) | F10F2SLC29A1 | |
| SCHEMBL19546836 | 0.74 | F10 (0.64) | F10F2SLC29A1PDE4APDE4B | |
| SCHEMBL19311594 | 0.73 | F10 (0.77) | F10F2SLC29A1 | |
| SCHEMBL16190022 | 0.73 | F10 (0.49) | F10F2SLC29A1PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014169845-A2 | 4,5-DIHYDRO-PYRAZOLO [3, 4-C] PYRID-2-ONES, PREPARATION METHOD AND APPLICATION THEREOF | 四川海思科制药有限公司 (CN) | 2014-10-23 | — | — | WO | disclosed |