Cyclohexylamine

Cyclohexylamine

SCHEMBL16192602

C1CC1.CCO[SiH](OCC)OCC.NC1CCCCC1

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 2/20 0.32
MMP1 P03956 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MMP2 P08253 1/20 0.30
SHBG P04278 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexylamine SCHEMBL28995358 1.00 MMP8 (0.32) MMP8MMP1ALDH1A1MMP2SHBG
Cyclohexylamine SCHEMBL16192520 0.98 MMP1 (0.31) MMP8MMP1ALDH1A1
SCHEMBL5050587 0.91 GNAI3 (0.30)
Cyclohexylamine SCHEMBL20210948 0.84 MMP1 (0.31) MMP8MMP1ALDH1A1
Cyclohexylamine SCHEMBL2701296 0.83 MMP1 (0.30) MMP8MMP1ALDH1A1
SCHEMBL3836344 0.81 ALDH1A1 (0.40) ALDH1A1SHBG
Cyclopropane SCHEMBL20694865 0.80
Cyclohexane SCHEMBL28994879 0.80
SCHEMBL1524356 0.80
Cyclooctane SCHEMBL28671573 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN claimed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US claimed
EP-3157970-B1 SILYLATED POLYURETHANES HUNTSMAN INT LLC (US) 2019-02-06 EP claimed
US-20170198084-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC 2017-07-13 US claimed
EP-2957582-A1 Isocyanate-based prepolymers HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 EP claimed
US-20220220247-A1 Composition Comprising Silylated Polymer HUNTSMAN INTERNATIONAL LLC 2022-07-14 US disclosed
CN-113966360-A Compositions comprising silylated polymers 亨茨曼国际有限公司 2022-01-21 CN disclosed
CN-106459362-B Silylated polyurethanes 亨茨曼国际有限公司 2020-10-13 CN disclosed
US-10351656-B2 Silylated polyurethanes HUNTSMAN INTERNATIONAL LLC (US) 2019-07-16 US disclosed
EP-3157970-B1 SILYLATED POLYURETHANES HUNTSMAN INT LLC (US) 2019-02-06 EP disclosed
EP-2989155-B1 COMPOSITION COMPRISING SILYLATED POLYMERS HUNTSMAN INT LLC (US) 2018-10-03 EP disclosed
US-9752013-B2 Composition comprising silylated polymers HUNTSMAN INTERNATIONAL LLC (US) 2017-09-05 US disclosed
US-20170198084-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC 2017-07-13 US disclosed
EP-2989155-A1 COMPOSITION COMPRISING SILYLATED POLYMERS Huntsman International LLC (US) 2016-03-02 EP disclosed
US-20160046793-A1 Composition Comprising Silylated Polymers HUNTSMAN INTERNATIONAL LLC 2016-02-18 US disclosed
EP-2957582-A1 Isocyanate-based prepolymers HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 EP disclosed
WO-2014173638-A1 COMPOSITION COMPRISING SILYLATED POLYMERS HUNTSMAN INTERNATIONAL LLC (US) 2014-10-30 WO disclosed
EP-2796493-A1 Composition comprising silylated polymers and polyhedral oligomeric metallo silsesquioxane HUNTSMAN INTERNATIONAL LLC (US) 2014-10-29 EP disclosed