Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SDCBP | O00560 | 6/20 | 0.35 |
| ▸ | SDC2 | P34741 | 6/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23482963 | 0.87 | MAPT (0.39) | ALOX15MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL24291608 | 0.86 | ALOX15 (0.40) | ALOX15MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL24289719 | 0.86 | ALOX15 (0.40) | ALOX15MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL25075338 | 0.85 | SDCBP (0.45) | ALOX15MAPTSMN1; SMN2KDM4ESDCBP | |
| SCHEMBL12942069 | 0.82 | ALOX15 (0.54) | ALOX15MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL15128633 | 0.81 | ERCC1 (0.42) | MAPTNPC1RAB9ASDCBPSDC2 | |
| SCHEMBL24288862 | 0.79 | KDM4E (0.42) | ALOX15MAPTSMN1; SMN2KDM4ENPC1 | |
| SCHEMBL21983039 | 0.79 | ITGB3 (0.39) | ALOX15MAPTSMN1; SMN2KDM4EITGB3 | |
| SCHEMBL21480827 | 0.79 | ITGB3 (0.39) | ALOX15MAPTSMN1; SMN2KDM4EITGB3 | |
| SCHEMBL24288936 | 0.79 | ALDH1A1 (0.45) | KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280237-A1 | SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER | 海创药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |
| WO-2014172429-A1 | COMBINATION THERAPY COMPRISING A TOR KINASE INHIBITOR AND AN IMID COMPOUND FOR TREATING CANCER | SIGNAL PHARMACEUTICALS, LLC (US) | 2014-10-23 | — | — | WO | disclosed |