SCHEMBL16196293

SCHEMBL16196293

CC(=O)c1cccc(-c2cccc(Br)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.53
MAP4K4 O95819 2/20 0.50
CSNK1G2 P78368 2/20 0.50
CLK4 Q9HAZ1 2/20 0.50
MKNK2 Q9HBH9 2/20 0.50
MAP4K5 Q9Y4K4 2/20 0.50
PARP1 P09874 1/20 0.50
PLK4 O00444 1/20 0.48
DCLK1 O15075 1/20 0.48
ROCK2 O75116 1/20 0.48
PRKD3 O94806 1/20 0.48
PAK4 O96013 1/20 0.48
CHEK2 O96017 1/20 0.48
INSR P06213 1/20 0.48
CDK1 P06493 1/20 0.48
FES P07332 1/20 0.48
ROS1 P08922 1/20 0.48
PDGFRB P09619 1/20 0.48
PDGFRA P16234 1/20 0.48
FER P16591 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30277354 0.88 PARP1 (0.63) MAOBPARP1MAOA
SCHEMBL3169 0.88 PARP1 (0.63) MAOBPARP1MAOA
SCHEMBL10389918 0.88 MAP4K4 (0.59) MAP4K4CSNK1G2CLK4MKNK2MAP4K5
SCHEMBL9293459 0.87 MAPT (0.62) MAOBPARP1HDAC2
SCHEMBL15887991 0.87 MAOA (0.53) MAOBMAP4K4CSNK1G2CLK4MKNK2
Ammonia Solution, Strong SCHEMBL27841907 0.86 PARP1 (0.61) MAOBPARP1MAOA
SCHEMBL28061958 0.86 PARP1 (0.61) MAOBPARP1MAOA
SCHEMBL2586835 0.86 KMO (0.59) MAP4K4CSNK1G2CLK4MKNK2MAP4K5
Water SCHEMBL28219304 0.84 PARP1 (0.59) MAOBPARP1MAOA
SCHEMBL783128 0.84 PARP1 (0.53) MAOBPARP1MAOAHDAC8KMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240083928-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-03-14 US disclosed
EP-2803671-B1 IRIDIUM COMPLEX COMPOUND, SOLUTION COMPOSITION CONTAINING IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE MITSUBISHI CHEM CORP (JP) 2019-05-01 EP disclosed
EP-2803671-B1 IRIDIUM COMPLEX COMPOUND, SOLUTION COMPOSITION CONTAINING IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE MITSUBISHI CHEM CORP (JP) 2019-05-01 EP disclosed
US-9799837-B2 Iridium complex compound, solution composition containing the compound, organic electroluminescent element, display, and lighting MITSUBISHI CHEMICAL CORPORATION (JP) 2017-10-24 US disclosed
US-9799837-B2 Iridium complex compound, solution composition containing the compound, organic electroluminescent element, display, and lighting MITSUBISHI CHEMICAL CORPORATION (JP) 2017-10-24 US disclosed
CN-104053664-B Iridium complex compound, solution composition containing iridium complex compound, organic electroluminescent element, display device, and lighting device 三菱化学株式会社 2016-07-06 CN disclosed
EP-2803671-A1 IRIDIUM COMPLEX COMPOUND, SOLUTION COMPOSITION CONTAINING IRIDIUM COMPLEX COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE Mitsubishi Chemical Corporation (JP) 2014-11-19 EP disclosed
US-20140319505-A1 IRIDIUM COMPLEX COMPOUND, SOLUTION COMPOSITION CONTAINING THE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY, AND LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-30 US disclosed
US-20140319505-A1 IRIDIUM COMPLEX COMPOUND, SOLUTION COMPOSITION CONTAINING THE COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY, AND LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240083928-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, JUND MAOB 325/4885MAP4K4 2712/4885CSNK1G2 4861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.