SCHEMBL783128

SCHEMBL783128

O=C(c1cccc(-c2cccc(Br)c2)c1)c1cccc(-c2cccc(Br)c2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.53
TDP1 Q9NUW8 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
ATM Q13315 1/20 0.50
HDAC8 Q9BY41 1/20 0.48
KMO O15229 1/20 0.48
RELA Q04206 1/20 0.48
HSD17B1 P14061 1/20 0.47
HSD17B2 P37059 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TP53 P04637 1/20 0.47
IDO1 P14902 1/20 0.46
METAP2 P50579 1/20 0.46
KMT2A Q03164 2/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
HPGD P15428 1/20 0.44
MEN1 O00255 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL782415 0.94 ATM (0.61) PARP1TDP1L3MBTL1ATMHDAC8
Benzophenone SCHEMBL28640629 0.88 ATM (0.57) PARP1TDP1L3MBTL1ATMHDAC8
SCHEMBL30153175 0.87 PARP1 (0.68) PARP1TDP1L3MBTL1ATMRELA
SCHEMBL241785 0.87 PARP1 (0.68) PARP1TDP1L3MBTL1ATMRELA
SCHEMBL10631830 0.86 RAB9A (0.51) PARP1TDP1L3MBTL1ATMHDAC8
SCHEMBL15772807 0.86 KMO (0.68) PARP1HDAC8KMOKMT2ANPC1
SCHEMBL30014390 0.86 KMO (0.68) PARP1HDAC8KMOKMT2ANPC1
Hydrochloric Acid SCHEMBL27869733 0.85 PARP1 (0.65) PARP1TDP1L3MBTL1ATMALDH1A1
SCHEMBL16196293 0.84 MAOB (0.53) PARP1HDAC8KMORELAMAOA
SCHEMBL10275793 0.83 KMO (0.55) PARP1TDP1L3MBTL1ATMHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10177312-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2019-01-08 US disclosed
US-10177312-B2 Compounds for electronic devices MERCK PATENT GMBH (DE) 2019-01-08 US disclosed
EP-2705550-B1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-07-05 EP disclosed
EP-2705550-B1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2017-07-05 EP disclosed
US-9537105-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-01-03 US disclosed
US-9537105-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-01-03 US disclosed
EP-2714841-B1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2016-06-22 EP disclosed
EP-2714841-B1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2016-06-22 EP disclosed
US-20150318478-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-11-05 US disclosed
US-20150318478-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2015-11-05 US disclosed
CN-103503188-A Compounds for electronic devices MERCK PATENT GMBH 2014-01-08 CN disclosed
WO-2012163465-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2012-12-06 WO disclosed
WO-2012163465-A1 ORGANIC ELECTROLUMINESCENCE DEVICE MERCK PATENT GMBH (DE) 2012-12-06 WO disclosed
WO-2012149999-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-08 WO disclosed
WO-2012149999-A1 COMPOUNDS FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-11-08 WO disclosed
CN-102448946-A Material for organic electroluminescent device MERCK PATENT GMBH 2012-05-09 CN disclosed
US-20120068170-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-03-22 US disclosed
US-20120068170-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-03-22 US disclosed
US-20120068170-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2012-03-22 US disclosed
WO-2010136109-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2010-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150318478-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO2B1, SLCO1B3, SLCO4C1 PARP1 1997/4885TDP1 3627/4885L3MBTL1 3941/4885
US-20120068170-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES SLCO2B1, SLCO1B3, SLCO4C1 PARP1 1997/4885TDP1 3627/4885L3MBTL1 3941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.