SCHEMBL1627720

SCHEMBL1627720

COc1cccc(F)c1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 6/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
KMT2A Q03164 1/20 0.50
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA4 P22748 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
CA14 Q9ULX7 1/20 0.48
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
AR P10275 1/20 0.44
KRAS P01116 2/20 0.44
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29669870 1.00 NFE2L2 (0.50) NFE2L2SMN1; SMN2KMT2ACA12CA1
SCHEMBL475141 0.85 ALDH1A1 (0.46) NFE2L2SMN1; SMN2KMT2ACA12CA1
SCHEMBL8118707 0.85 KMT2A (0.46) NFE2L2SMN1; SMN2KMT2ACA12CA1
SCHEMBL1848425 0.83 KMT2A (0.45) NFE2L2SMN1; SMN2KMT2ACA12CA1
SCHEMBL931127 0.83 KMT2A (0.41) NFE2L2SMN1; SMN2KMT2ACA12CA1
SCHEMBL25434306 0.82 CA1 (0.61) NFE2L2SMN1; SMN2KMT2ACA12CA1
SCHEMBL151213 0.82 CA1 (0.61) NFE2L2SMN1; SMN2KMT2ACA12CA1
SCHEMBL27753904 0.82 CA1 (0.61) NFE2L2SMN1; SMN2KMT2ACA12CA1
SCHEMBL2035810 0.81 L3MBTL1 (0.53) NFE2L2SMN1; SMN2KMT2ATDP1L3MBTL1
SCHEMBL2033183 0.81 RPS6KA2 (0.41) NFE2L2KMT2ACA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1979979-A1 ADDITIVES FOR NON-AQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY USING THE SAME LG Chem, Ltd. (KR) 2008-10-15 EP claimed
WO-2007083917-A1 ADDITIVES FOR NON-AQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY USING THE SAME LG CHEM, LTD. (KR) 2007-07-26 WO claimed
US-20070166609-A1 ADDITIVES FOR NON-AQUEOUS ELECTROLYTE AND LITHIUM SECONDARY BATTERY USING THE SAME LG CHEM, LTD. (KR) 2007-07-19 US claimed
US-20250361253-A1 STING AGONIST COMPOUNDS SUTRO BIOPHARMA INC (US) 2025-11-27 US disclosed
EP-4536672-A1 STING AGONIST COMPOUNDS Sutro Biopharma, Inc. (US) 2025-04-16 EP disclosed
EP-4523755-A2 QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS F. Hoffmann-La Roche AG (CH) 2025-03-19 EP disclosed
EP-4360713-B1 QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS HOFFMANN LA ROCHE (CH) 2024-10-30 EP disclosed
CN-118255772-A Quinazoline derivatives as antitumor agents 苏州赞荣医药科技有限公司 2024-06-28 CN disclosed
EP-4389752-A1 CAMPTOTHECIN DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF Simcere Zaiming Pharmaceutical Co., Ltd. (CN) 2024-06-26 EP disclosed
EP-4360713-A2 QUINAZOLINE DERIVATIVES AS ANTITUMOR AGENTS F. Hoffmann-La Roche AG (CH) 2024-05-01 EP disclosed
CN-117412953-A Axl inhibitors 微境生物医药科技(上海)有限公司 2024-01-16 CN disclosed
WO-1994029243-A1 SYNTHESIS OF SUBSTITUTED TRIPHENYLENES, USEFUL AS DISCOTIC LIQUID CRYSTALS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-12-22 WO disclosed
US-4855476-A 3,4-DIBENZYLOXY-5-FLUOROBENZYLCYANIDE FROM 2-FLUORO-6-METHOXYP HENOL OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1989-08-08 US disclosed
US-4737504-A INCREASE BETA-2 ADRENERGIC ACTIVITY WHILE DECREASING BETA-1; CARDIOVASCULAR AND RESPIRATORY DISORDERS OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) 1988-04-12 US disclosed
US-4479901-A Fluorination of carbanions with N-fluoro-N-alkylsulfonamides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-30 US disclosed
EP-0080012-A1 6-Chloro-3-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine, its acid addition salts and its use as an intermediate SMITHKLINE BECKMAN CORPORATION (US) 1983-06-01 EP disclosed
EP-0007070-B1 2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS HAVING DOPAMINE RECEPTOR BLOCKING ACTIVITY SMITHKLINE BECKMAN CORPORATION (US) 1983-01-19 EP disclosed
US-4265890-A ANTIPSYCHOTIC, ANTIEMETICS SMITHKLINE CORPORATION (US) 1981-05-05 US disclosed
EP-0007070-A1 2,3,4,5-Tetrahydro-1H-3-Benzazepines, process for their production and pharmaceutical compositions having dopamine receptor blocking activity SMITHKLINE BECKMAN CORPORATION (US) 1980-01-23 EP disclosed
US-3976695-A Halogen substituted α-(aminoalkyl)-3,4-dihydroxybenzyl alcohols SMITHKLINE CORPORATION (US) 1976-08-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250361253-A1 STING AGONIST COMPOUNDS STING1, CGAS, MAVS NFE2L2 1578/4885SMN1; SMN2 2004/4885KMT2A 3627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.