Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 6/20 | 0.41 |
| ▸ | CNR2 | P34972 | 5/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16197681 | 0.86 | ALOX5 (0.39) | MTNR1AMTNR1BHTR2AHRH1ALOX5 | |
| SCHEMBL329180 | 0.83 | MTNR1A (0.58) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL16197845 | 0.80 | MTNR1A (0.49) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| Glycine SCHEMBL27555842 | 0.80 | MTNR1A (0.51) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL1321258 | 0.77 | MTNR1A (0.54) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| Hydrochloric Acid SCHEMBL5311014 | 0.75 | MTNR1A (0.53) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL3905618 | 0.74 | HRH1 (0.58) | MTNR1AMTNR1BHTR2AHRH1ALOX5 | |
| SCHEMBL5662442 | 0.72 | MAOA (0.32) | — | |
| SCHEMBL5846249 | 0.72 | KCNH2 (0.58) | MTNR1AMTNR1BCNR1CNR2EPHX2 | |
| SCHEMBL663798 | 0.70 | CNR1 (0.62) | MTNR1AMTNR1BCNR1CNR2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2989119-A1 | USE OF INHIBITORY PEPTIDES FOR THE TREATMENT OF INFLAMMATORY DISEASES | Yeda Research and Development Co., Ltd. (IL) | 2016-03-02 | — | — | EP | disclosed |
| WO-2014174520-A1 | USE OF INHIBITORY PEPTIDES FOR THE TREATMENT OF INFLAMMATORY DISEASES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2014-10-30 | — | — | WO | disclosed |