Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | MC3R | P41968 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310631 | 0.93 | BCAT2 (0.49) | BCAT2GRIN1GRIN2ACYP2D6CYP1A2 | |
| SCHEMBL181573 | 0.89 | GRIN1 (0.52) | BCAT2GRIN1GRIN2ACYP2D6SMN1; SMN2 | |
| SCHEMBL16197845 | 0.84 | MTNR1A (0.49) | — | |
| SCHEMBL5927838 | 0.82 | BCAT2 (0.35) | BCAT2GRIN1GRIN2ACYP2D6CYP1A2 | |
| SCHEMBL16197681 | 0.79 | ALOX5 (0.39) | BCAT2GRIN1GRIN2ACYP2C19KDM4E | |
| SCHEMBL662614 | 0.78 | TACR1 (0.48) | BCAT2LMNACA1CA2 | |
| SCHEMBL1321258 | 0.76 | MTNR1A (0.54) | — | |
| SCHEMBL164711 | 0.75 | — | — | |
| SCHEMBL5662445 | 0.75 | MAOA (0.44) | CYP1A2LMNACA1CA2KDM4E | |
| SCHEMBL13917984 | 0.75 | GRIN1 (0.58) | GRIN1GRIN2ACYP2D6KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2989119-A1 | USE OF INHIBITORY PEPTIDES FOR THE TREATMENT OF INFLAMMATORY DISEASES | Yeda Research and Development Co., Ltd. (IL) | 2016-03-02 | — | — | EP | disclosed |
| WO-2014174520-A1 | USE OF INHIBITORY PEPTIDES FOR THE TREATMENT OF INFLAMMATORY DISEASES | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2014-10-30 | — | — | WO | disclosed |