Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20865760 | 0.88 | BCHE (0.47) | BCHEACHEHTR3AKMT2ACYP11B2 | |
| SCHEMBL830534 | 0.82 | ACHE (0.47) | BCHEACHEKMT2AHRH3 | |
| SCHEMBL28573718 | 0.82 | HTR3A (0.44) | HTR3APIK3CAPIK3CBPIK3CGKMT2A | |
| SCHEMBL833240 | 0.76 | MAPT (0.52) | BCHEACHEPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17531769 | 0.73 | CYP11B2 (0.40) | HTR3APIK3CAPIK3CBPIK3CGKMT2A | |
| SCHEMBL16198209 | 0.71 | ALDH1A1 (0.38) | KMT2ABACE1NUDT1TBXA2R | |
| SCHEMBL16208380 | 0.71 | ALDH1A1 (0.38) | KMT2ABACE1NUDT1TBXA2R | |
| SCHEMBL28915375 | 0.70 | HTR3A (0.44) | HTR3AKMT2ACYP11B2HRH3 | |
| SCHEMBL27407454 | 0.70 | HTR3A (0.44) | HTR3AKMT2ACYP11B2HRH3 | |
| SCHEMBL8810696 | 0.69 | BCHE (0.52) | BCHEACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014176258-A1 | COMPOUNDS USEFUL AS ANTIBIOTIC TOLERANCE INHIBITORS | THE GENERAL HOSPITAL CORPORATION (US) | 2014-10-30 | — | — | WO | disclosed |