SCHEMBL16199823

SCHEMBL16199823

CCCC[SiH](O)CCCN

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.46
ALDH1A1 P00352 2/20 0.46
TSHR P16473 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
EPHX1 P07099 1/20 0.46
GABBR2 O75899 2/20 0.38
GABBR1 Q9UBS5 2/20 0.38
GABRR1 P24046 1/20 0.38
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
LMNA P02545 1/20 0.30
NFKB1 P19838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1828102 0.86 TSHR (0.40) ALDH1A1TSHRMEN1KMT2ANOS3
SCHEMBL1829570 0.80
SCHEMBL8055855 0.80
Benzene SCHEMBL28857166 0.78 TSHR (0.33) ALDH1A1TSHRKMT2ALMNA
Butylamine SCHEMBL15823985 0.77
SCHEMBL15520743 0.77 TSHR (0.44) DNM1ALDH1A1TSHRMEN1KMT2A
SCHEMBL15808698 0.75 DNM1 (0.71) DNM1ALDH1A1TSHRMEN1KMT2A
SCHEMBL17024461 0.75 TSHR (0.50) DNM1ALDH1A1TSHRMEN1KMT2A
SCHEMBL1829074 0.75
SCHEMBL17088165 0.75 TSHR (0.50) DNM1ALDH1A1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2473849-B1 NANOPORED SILICON NITRIDE CHIP FOR THE ANALYSIS OF GENE EXPRESSION PROFILES UNIV DEGLI STUDI GENOVA (IT) 2014-10-29 EP disclosed