Benzene

Benzene

SCHEMBL28857166

CCCC[SiH](O)CCCC.c1ccccc1

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.33
LMNA P02545 2/20 0.33
ALDH1A1 P00352 1/20 0.33
PCSK9 Q8NBP7 1/20 0.33
PTGS2 P35354 1/20 0.32
CHRM2 P08172 2/20 0.32
ADRA2A P08913 2/20 0.32
ADORA3 P0DMS8 2/20 0.32
CHRM1 P11229 2/20 0.32
ACHE P22303 2/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
ABCB11 O95342 1/20 0.32
ESR1 P03372 1/20 0.32
PGR P06401 1/20 0.32
HTR1A P08908 1/20 0.32
DRD1 P21728 1/20 0.32
TBXA2R P21731 1/20 0.32
PTGS1 P23219 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1828102 0.91 TSHR (0.40) TSHRLMNAALDH1A1AKR1B1SMN1; SMN2
SCHEMBL1829570 0.85
Benzene SCHEMBL28857164 0.82 TSHR (0.33) TSHRLMNAALDH1A1PCSK9PTGS2
SCHEMBL15520743 0.81 TSHR (0.44) TSHRLMNAALDH1A1AKR1B1SMN1; SMN2
Benzene SCHEMBL28857089 0.81
SCHEMBL1829074 0.79
SCHEMBL17088165 0.79 TSHR (0.50) TSHRLMNAALDH1A1SMN1; SMN2THRB
SCHEMBL17024461 0.79 TSHR (0.50) TSHRLMNAALDH1A1SMN1; SMN2THRB
SCHEMBL16199823 0.78 DNM1 (0.46) TSHRLMNAALDH1A1KMT2A
SCHEMBL9745147 0.78 TP53 (0.39) PCSK9SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115151868-A Photosensitive resin composition, method for sorting photosensitive resin composition, method for producing patterned cured film, and method for producing semiconductor device 昭和电工材料株式会社 2022-10-04 CN disclosed