SCHEMBL16201003

SCHEMBL16201003

CN(C)c1ccc(-c2ccc3c4c(cccc24)-c2ccccc2-3)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CRHBP P24387 1/20 0.44
▸ CRHR2 Q13324 1/20 0.44
▸ KEAP1 Q14145 1/20 0.44
▸ NFE2L2 Q16236 1/20 0.44
▸ KDM1A O60341 1/20 0.42
▸ MAPT P10636 5/20 0.41
▸ KDM4E B2RXH2 4/20 0.41
▸ TSHR P16473 4/20 0.41
▸ ALDH1A1 P00352 3/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ HPGD P15428 3/20 0.41
▸ HIF1A Q16665 2/20 0.41
▸ LMNA P02545 2/20 0.41
▸ CYP1A2 P05177 2/20 0.41
▸ CYP3A4 P08684 2/20 0.41
▸ CYP2D6 P10635 2/20 0.41
▸ CYP2C9 P11712 2/20 0.41
▸ CYP2C19 P33261 2/20 0.41
▸ GLA P06280 1/20 0.41
▸ RECQL P46063 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20821546 0.85 TSHR (0.42) KDM1AMAPTKDM4ETSHRALDH1A1
SCHEMBL9888927 0.82 CRHBP (0.44) CRHBPCRHR2KEAP1NFE2L2MAPT
SCHEMBL12249595 0.81 ENPP3 (0.49) KDM1AMAPTKDM4ETSHRALDH1A1
SCHEMBL23546684 0.81 CRHBP (0.43) CRHBPCRHR2KEAP1NFE2L2KDM1A
SCHEMBL2033903 0.78 CRHBP (0.56) CRHBPCRHR2KEAP1NFE2L2MAPT
SCHEMBL31107072 0.78 CRHBP (0.56) CRHBPCRHR2KEAP1NFE2L2MAPT
SCHEMBL19698857 0.78 ALDH1A1 (0.58) MAPTKDM4ETSHRALDH1A1SMN1; SMN2
SCHEMBL17012199 0.77 CRHBP (0.40) CRHBPCRHR2KEAP1NFE2L2MAPT
SCHEMBL17012373 0.77 CRHBP (0.40) CRHBPCRHR2KEAP1NFE2L2MAPT
SCHEMBL23764165 0.77 MAPT (0.38) CRHBPCRHR2KEAP1NFE2L2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9298115-B2 Electrophotographic photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-03-29 — — US disclosed
US-9298115-B2 Electrophotographic photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-03-29 — — US disclosed
US-20140322637-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-10-30 — — US disclosed
US-20140322637-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-10-30 — — US disclosed
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