Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 2/20 | 0.36 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 9/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.31 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16201234 | 0.91 | PRMT6 (0.46) | TRPV3PRMT6PRMT1PRMT8PRMT3 | |
| SCHEMBL16204239 | 0.89 | PRMT1 (0.45) | TRPV3PRMT6PRMT1PRMT8PRMT3 | |
| SCHEMBL16201443 | 0.87 | PRMT6 (0.45) | PRMT6PRMT1PRMT8S1PR1S1PR3 | |
| SCHEMBL16125845 | 0.86 | CTSS (0.43) | PRMT6PRMT1PRMT8PRMT3CARM1 | |
| SCHEMBL16201363 | 0.83 | PRMT6 (0.39) | TRPV3PRMT6PRMT1PRMT8PRMT3 | |
| SCHEMBL16125829 | 0.80 | PRMT6 (0.43) | PRMT6PRMT1PRMT8PRMT3CARM1 | |
| SCHEMBL16201289 | 0.80 | PRMT6 (0.45) | PRMT6PRMT1PRMT8PRMT3CARM1 | |
| SCHEMBL16201340 | 0.79 | TDO2 (0.33) | — | |
| SCHEMBL16201371 | 0.77 | NPSR1 (0.39) | PRMT6PRMT1PRMT8PRMT3CARM1 | |
| SCHEMBL16201384 | 0.76 | PRMT3 (0.40) | PRMT6PRMT1PRMT8PRMT3CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9346761-B2 | Arginine methyltransferase inhibitors and uses thereof | Epizyme, Inc. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20140323537-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | Epizyme, Inc. (US) | 2014-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323537-A1 | ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF | PRMT1, PRMT3, PRMT5 | TRPV3 4840/4885PRMT6 4/4885PRMT1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.