SCHEMBL16202015

SCHEMBL16202015

C=CCO/N=C(\C)c1cc(C)c(C)cc1C

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.41
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
RXRG P48443 1/20 0.41
LMNA P02545 2/20 0.37
MAPT P10636 1/20 0.34
PTBP1 P26599 1/20 0.31
PPARG P37231 1/20 0.30
PPARA Q07869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16202030 0.82 RXRA (0.36) SMN1; SMN2RXRARXRBRXRGLMNA
SCHEMBL16202031 0.81
SCHEMBL16202013 0.81 SMN1; SMN2 (0.48) SMN1; SMN2RXRARXRBRXRGLMNA
SCHEMBL16202066 0.81
SCHEMBL9138955 0.80 SMN1; SMN2 (0.35) SMN1; SMN2RXRARXRBRXRGLMNA
SCHEMBL3192262 0.78 RXRA (0.33) SMN1; SMN2RXRARXRBRXRGLMNA
SCHEMBL3192253 0.78 RXRA (0.33) SMN1; SMN2RXRARXRBRXRGLMNA
SCHEMBL3192249 0.78 RXRA (0.33) SMN1; SMN2RXRARXRBRXRGLMNA
SCHEMBL17218743 0.75 SMN1; SMN2 (0.46) SMN1; SMN2RXRARXRBRXRGLMNA
SCHEMBL15851190 0.75 SMN1; SMN2 (0.46) SMN1; SMN2RXRARXRBRXRGLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2016-09-01 US disclosed
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-26 US disclosed
US-20160145202-A1 Strobilurin Type Compounds for Combating Phytopathogenic Fungi BASF SE (DE) 2016-05-26 US disclosed
US-20160122327-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-05 US disclosed
US-9271501-B2 Use of strobilurin type compounds for combating phytopathogenic fungi resistant to QO inhibitors BASF SE (DE) 2016-03-01 US disclosed
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2014-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160122327-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI SNX1, DPM1, SNU13 SMN1; SMN2 2653/4885RXRA 4465/4885RXRB 4450/4885
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI DPM1, CROCC, SNX1 SMN1; SMN2 3486/4885RXRA 4379/4885RXRB 4400/4885
US-20160145202-A1 Strobilurin Type Compounds for Combating Phytopathogenic Fungi DPM1, CROCC, SNX1 SMN1; SMN2 3486/4885RXRA 4379/4885RXRB 4400/4885
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB SMN1; SMN2 2724/4885RXRA 4724/4885RXRB 4037/4885
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB SMN1; SMN2 2724/4885RXRA 4724/4885RXRB 4037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.