Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 4/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13245005 | 0.88 | ALDH1A1 (0.54) | ALDH1A1ATMMEN1KMT2AKIF11 | |
| SCHEMBL3629228 | 0.84 | ALDH1A1 (0.65) | ALDH1A1ATMMEN1CYP1A2HPGD | |
| SCHEMBL7360321 | 0.81 | NR4A2 (0.50) | ALDH1A1MEN1CYP1A2HPGDALOX12 | |
| SCHEMBL19518702 | 0.79 | CYP1A2 (0.74) | ALDH1A1MEN1CYP1A2HPGDALOX12 | |
| SCHEMBL16205922 | 0.79 | NR4A2 (0.67) | ALDH1A1ATMNR4A2PIM1PIM3 | |
| SCHEMBL214780 | 0.77 | ALDH1A1 (0.61) | ALDH1A1ATMHPGDNR4A2PIM1 | |
| SCHEMBL15652258 | 0.77 | ALDH1A1 (0.61) | ALDH1A1ATMMEN1CYP1A2HPGD | |
| SCHEMBL26204498 | 0.76 | NR4A2 (0.65) | ALDH1A1ATMNR4A2PIM1PIM3 | |
| SCHEMBL8889647 | 0.76 | ALDH1A1 (0.59) | ALDH1A1ATMNR4A2PIM1PIM3 | |
| SCHEMBL3660284 | 0.75 | MAPT (0.69) | ALDH1A1ATMMEN1KMT2ANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150336958-A1 | SUBSTITUTED ACETYL-COA CARBOXYLASE INHIBITORS | PFIZER INC. (US) | 2015-11-26 | — | — | US | disclosed |
| US-20140323730-A1 | SUBSTITUTED ACETYL-COA CARBOXYLASE INHIBITORS | PFIZER (US) | 2014-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336958-A1 | SUBSTITUTED ACETYL-COA CARBOXYLASE INHIBITORS | ACACA, ACACB, ACAT1 | ALDH1A1 96/4885ATM 1641/4885MEN1 3985/4885 |
| US-20140323730-A1 | SUBSTITUTED ACETYL-COA CARBOXYLASE INHIBITORS | ACACA, ACACB, ACAT1 | ALDH1A1 105/4885ATM 1673/4885MEN1 3794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.