SCHEMBL16206014

SCHEMBL16206014

COc1ccc(-c2cc(OCc3c(C)cccc3-n3nnn(C)c3=O)ccc2F)cc1

nearest known ligand 0.42

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 7/20 0.42
GYS1 P13807 9/20 0.39
ANO1 Q5XXA6 1/20 0.39
STIM1 Q13586 2/20 0.38
ORAI1 Q96D31 2/20 0.38
PPARD Q03181 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17614599 0.94 GYS1 (0.40) FFAR1GYS1ANO1STIM1ORAI1
SCHEMBL17614598 0.94 ANO1 (0.40) FFAR1GYS1ANO1STIM1ORAI1
SCHEMBL16206015 0.93 FFAR1 (0.41) FFAR1STIM1ORAI1PPARD
SCHEMBL17614597 0.93 GYS1 (0.37) FFAR1GYS1ANO1
SCHEMBL16206009 0.93 FFAR1 (0.37) FFAR1GYS1ANO1STIM1ORAI1
SCHEMBL16205972 0.92 GYS1 (0.39) FFAR1GYS1ANO1PPARD
SCHEMBL16206012 0.90 FFAR1 (0.37) FFAR1ANO1STIM1ORAI1
SCHEMBL16206131 0.90 SYK (0.41) GYS1STIM1ORAI1
SCHEMBL17614596 0.89 FFAR4 (0.37) FFAR1GYS1ANO1
SCHEMBL17614595 0.89 FFAR1 (0.34) FFAR1GYS1ANO1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2990404-B1 TETRAZOLINONE COMPOUND AND USE OF SAME SUMITOMO CHEMICAL CO (JP) 2020-05-27 EP disclosed
US-9867372-B2 Tetrazolinone compound and use of same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-16 US disclosed
US-20160081339-A1 TETRAZOLINONE COMPOUND AND USE OF SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-03-24 US disclosed
WO-2014175465-A1 TETRAZOLINONE COMPOUND AND USE OF SAME 住友化学株式会社 (JP) 2014-10-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160081339-A1 TETRAZOLINONE COMPOUND AND USE OF SAME MT-CO1, SOD1, MT-CO2 FFAR1 1688/4885GYS1 1117/4885ANO1 2082/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.