Homosalate

Homosalate

SCHEMBL2016281

CC1CC(OC(=O)c2ccccc2O)CC(C)(C)C1.O=C(c1ccccc1)c1ccccc1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.86
CYP3A4 P08684 3/20 0.86
CYP2C9 P11712 3/20 0.86
ALDH1A1 P00352 2/20 0.86
CYP2C19 P33261 2/20 0.86
CYP1A2 P05177 1/20 0.86
NR1I2 O75469 1/20 0.54
ABCB11 O95342 1/20 0.54
GAA P10253 1/20 0.43
TSHR P16473 4/20 0.39
PLA2G1B P04054 1/20 0.38
ATG4B Q9Y4P1 1/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
BCHE P06276 1/20 0.37
CHRNA7 P36544 2/20 0.37
HTR3E A5X5Y0 1/20 0.37
HTR3B O95264 1/20 0.37
HTR3A P46098 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Homosalate SCHEMBL2808104 0.94 ALDH1A1 (0.97) LMNACYP3A4CYP2C9ALDH1A1CYP2C19
Homosalate SCHEMBL8106557 0.93 LMNA (0.86) LMNACYP3A4CYP2C9ALDH1A1CYP2C19
Homosalate SCHEMBL8840156 0.93 ALDH1A1 (0.86) LMNACYP3A4CYP2C9ALDH1A1CYP2C19
Homosalate SCHEMBL29356436 0.93 ALDH1A1 (1.00) LMNACYP3A4CYP2C9ALDH1A1CYP2C19
Homosalate SCHEMBL16207 0.93 ALDH1A1 (1.00) LMNACYP3A4CYP2C9ALDH1A1CYP2C19
Homosalate SCHEMBL3634890 0.93 ALDH1A1 (1.00) LMNACYP3A4CYP2C9ALDH1A1CYP2C19
Homosalate SCHEMBL8863191 0.92 LMNA (0.84) LMNACYP3A4CYP2C9ALDH1A1CYP2C19
Homosalate SCHEMBL1004720 0.87 LMNA (0.68) LMNACYP3A4CYP2C9ALDH1A1CYP2C19
Homosalate SCHEMBL9452512 0.86 LMNA (0.86) LMNACYP3A4CYP2C9ALDH1A1CYP2C19
Homosalate SCHEMBL9099946 0.86 ALDH1A1 (0.86) LMNACYP3A4CYP2C9ALDH1A1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2515772-A1 COUPLING EMULSIONS FOR USE WITH ULTRASOUND DEVICES Avon Products, Inc. (US) 2012-10-31 EP disclosed
US-20120259252-A1 Coupling Emulsions for Use With Ultrasound Devices AVON PRODUCTS, INC. (US) 2012-10-11 US disclosed
WO-2011078905-A1 COUPLING EMULSIONS FOR USE WITH ULTRASOUND DEVICES AVON PRODUCTS, INC. (US) 2011-06-30 WO disclosed