Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 4/20 | 0.39 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CD69 | Q07108 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14629625 | 0.88 | ESR1 (0.33) | ESR1ESR2TSHRALDH1A1TDP1 | |
| SCHEMBL16201611 | 0.86 | MAPK1 (0.36) | ESR1ESR2TSHRRAB9AALDH1A1 | |
| SCHEMBL14011198 | 0.85 | GLA (0.37) | ESR1ESR2TSHRALDH1A1TDP1 | |
| SCHEMBL19354009 | 0.80 | ALDH1A1 (0.34) | ESR1ESR2HPGDALDH1A1KDM4E | |
| SCHEMBL13753107 | 0.78 | POLB (0.46) | POLBHTR1DHTR1BELANECD69 | |
| SCHEMBL12401801 | 0.74 | POLB (0.43) | POLBHTR1DHTR1BELANECD69 | |
| SCHEMBL14140023 | 0.73 | — | — | |
| SCHEMBL14629626 | 0.73 | NPC1 (0.37) | TSHRRAB9AALDH1A1LMNAMAPK1 | |
| SCHEMBL14701793 | 0.72 | VDR (0.31) | ELANE | |
| SCHEMBL16201698 | 0.71 | MAPK1 (0.37) | POLBESR1ESR2RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012572-B2 | Polyphenylene ether oligomer and article employing the same | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2015-04-21 | — | — | US | disclosed |
| US-20140323666-A1 | POLYPHENYLENE ETHER OLIGOMER AND ARTICLE EMPLOYING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2014-10-30 | — | — | US | disclosed |