SCHEMBL14701793

SCHEMBL14701793

CCC(C)(C)Oc1c(C)cc(C(C)(C)c2cc(C)c(OC(=O)C(C)(C)CC)c(C)c2)cc1C

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
VDR P11473 1/20 0.31
RIPK1 Q13546 1/20 0.30
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19827499 0.90 BRD4 (0.31) RIPK1ELANE
SCHEMBL14701719 0.87 PPARA (0.35) ELANE
SCHEMBL17068814 0.80 KDM4E (0.38) RIPK1ELANE
SCHEMBL13661693 0.79 MAPT (0.43)
SCHEMBL25968669 0.77 RIPK1 (0.33) VDRRIPK1ELANE
SCHEMBL12040652 0.77 VDR (0.42) VDR
SCHEMBL25596263 0.75 HSD11B1 (0.34) VDR
SCHEMBL26078923 0.75 LMNA (0.39)
SCHEMBL19354009 0.75 ALDH1A1 (0.34) VDR
SCHEMBL14015405 0.75 ELANE (0.35) RIPK1ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130040234-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, MANUFACTURING METHOD THEREFOR AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2013-02-14 US disclosed