Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | ATG4B | Q9Y4P1 | 8/20 | 0.58 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17076650 | 0.80 | ATG4B (0.51) | LMNAATG4BMAPK8MAPK9MEN1 | |
| SCHEMBL18529277 | 0.80 | ATG4B (0.54) | LMNAATG4BMAPK8MAPK9MEN1 | |
| SCHEMBL1392634 | 0.78 | LMNA (0.92) | LMNAATG4BMEN1NPC1RAB9A | |
| SCHEMBL1394642 | 0.77 | ATG4B (0.85) | LMNAATG4B | |
| SCHEMBL4884971 | 0.77 | LMNA (0.90) | LMNAATG4BMEN1NPC1RAB9A | |
| SCHEMBL7193648 | 0.76 | ATG4B (0.52) | LMNAATG4BMEN1NPC1RAB9A | |
| SCHEMBL1395039 | 0.76 | LMNA (1.00) | LMNAATG4BMEN1NPC1RAB9A | |
| SCHEMBL16535027 | 0.76 | ATG4B (0.46) | LMNAATG4BMEN1NPC1RAB9A | |
| SCHEMBL13461165 | 0.74 | NPC1 (0.54) | LMNAATG4BMEN1NPC1RAB9A | |
| SCHEMBL4733311 | 0.74 | LMNA (0.51) | LMNAATG4BMAPK8MAPK9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408770-B1 | BROAD SPECTRUM BENZOTHIOPHENE-NITROTHIAZOLIDE AND OTHER ANTIMICROBIALS | Univ Virginia Patent Found (US) | 2014-11-05 | — | — | EP | disclosed |