Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | LDHB | P07195 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22703438 | 0.90 | TDP1 (0.46) | ALDH1A1SMN1; SMN2FOLH1KDM4ELDHA | |
| SCHEMBL7930737 | 0.87 | MEN1 (0.50) | FOLH1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL23354313 | 0.87 | KMT2A (0.50) | ALDH1A1FOLH1KMT2AMEN1DHODH | |
| SCHEMBL23911685 | 0.87 | FOLH1 (0.52) | FOLH1KMT2ARAB9AHSD17B10MEN1 | |
| SCHEMBL3901924 | 0.84 | CA12 (0.62) | ALDH1A1SMN1; SMN2KDM4EKMT2ANPC1 | |
| SCHEMBL14825546 | 0.83 | ABCB1 (0.46) | ALDH1A1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL593127 | 0.82 | FOLH1 (0.61) | ALDH1A1SMN1; SMN2FOLH1KMT2AHPGD | |
| SCHEMBL593809 | 0.81 | FOLH1 (0.49) | FOLH1LDHALDHBKMT2ADHODH | |
| SCHEMBL867477 | 0.81 | MYC (0.47) | ALDH1A1SMN1; SMN2KDM4EAKR1C3KMT2A | |
| SCHEMBL4621115 | 0.80 | LDHA (0.46) | ALDH1A1SMN1; SMN2KDM4ELDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140330018-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-11-06 | — | — | US | disclosed |
| US-20140330018-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-11-06 | — | — | US | disclosed |
| US-20140330018-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140330018-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | TERT, CYP19A1, MPO | ALDH1A1 109/4885SMN1; SMN2 1606/4885FOLH1 2253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.