Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA7 | P43166 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.48 |
| ▸ | HNF4A | P41235 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL593127 | 0.90 | FOLH1 (0.61) | FOLH1CA12CA1CA2CA7 | |
| SCHEMBL16211069 | 0.87 | ALDH1A1 (0.46) | FOLH1CA12CA1CA2CA7 | |
| SCHEMBL9550356 | 0.87 | HNF4A (0.55) | FOLH1CA12CA1CA2CA7 | |
| SCHEMBL13966792 | 0.85 | MMP9 (0.55) | FOLH1CA12CA1CA2CA7 | |
| SCHEMBL1362671 | 0.84 | HNF4A (0.57) | FOLH1CA12CA1CA2CA7 | |
| SCHEMBL29669745 | 0.83 | HNF4A (0.61) | FOLH1HNF4ACDC25BATMKMT2A | |
| SCHEMBL9019636 | 0.83 | HNF4A (0.61) | FOLH1HNF4ACDC25BATMKMT2A | |
| SCHEMBL1353530 | 0.83 | HNF4A (0.61) | FOLH1HNF4ACDC25BATMKMT2A | |
| SCHEMBL21879681 | 0.83 | CDC25B (0.50) | FOLH1HNF4ACDC25BATMKMT2A | |
| SCHEMBL593309 | 0.82 | CYP2C8 (0.51) | FOLH1CYP2C8DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11142500-B2 | Nanohoop compound embodiments comprising meta-substitution and molecular systems comprising the same | UNIVERSITY OF OREGON (US) | 2021-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11142500-B2 | Nanohoop compound embodiments comprising meta-substitution and molecular systems comprising the same | MYC, KRAS, NRAS | FOLH1 4292/4885CA12 1312/4885CA1 2272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.