Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | CCR8 | P51685 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15773584 | 0.84 | GRM5 (0.38) | GRM5CCR1CCR5CCR8HDAC6 | |
| SCHEMBL9151348 | 0.81 | CYP11B2 (0.66) | CYP11B1CYP11B2 | |
| SCHEMBL15605539 | 0.79 | CYP11B2 (0.40) | GRM5CCR1CCR5CCR8HDAC6 | |
| SCHEMBL9511667 | 0.78 | TRPV4 (0.42) | CYP11B1CYP11B2EGLN2TRPV4 | |
| SCHEMBL13483666 | 0.76 | CCR1 (0.71) | GRM5CCR1CCR5CCR8HDAC6 | |
| SCHEMBL19243068 | 0.76 | CCR1 (0.54) | CCR1CCR5CCR8HDAC6CYP11B1 | |
| SCHEMBL12012492 | 0.75 | TRPV4 (0.47) | CYP11B1CYP11B2CYP2A6EGLN2TRPV4 | |
| SCHEMBL14681239 | 0.75 | CCR1 (0.48) | GRM5CCR1CCR5CCR8HDAC6 | |
| SCHEMBL9506490 | 0.75 | CYP11B1 (0.45) | CYP11B1CYP11B2EGLN2TRPV4 | |
| SCHEMBL24137558 | 0.75 | CCR1 (0.52) | GRM5CCR1CCR5CCR8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2799516-A1 | LIQUID CRYSTAL MATERIAL OF SMECTIC PHASE IN HIGH SCATTERING STATE AND DISPLAY DEVICE THEREOF | Halation Photonics Corporation (CN) | 2014-11-05 | — | — | EP | disclosed |