Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.45 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1705873 | 0.83 | TPMT (0.50) | ALDH1A1ERN1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL16207603 | 0.83 | PTGER1 (0.60) | NR1H4KMT2AMEN1ALDH1A1 | |
| SCHEMBL30008748 | 0.83 | PTGER1 (0.60) | NR1H4KMT2AMEN1ALDH1A1 | |
| SCHEMBL28669741 | 0.77 | ALDH1A1 (0.64) | HCAR3ALDH1A1ERN1AKR1C3AKR1C2 | |
| SCHEMBL12765327 | 0.76 | PTPN11 (0.52) | PTPN11NR1H4 | |
| SCHEMBL1749792 | 0.75 | PLA2G4B (0.74) | PLA2G4BHCAR3XDHALDH1A1AKR1C3 | |
| SCHEMBL30923227 | 0.75 | MAPT (0.48) | PTPN11PLA2G4BKMT2AMEN1ALDH1A1 | |
| SCHEMBL408308 | 0.75 | ERN1 (0.59) | ALDH1A1ERN1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL31415060 | 0.75 | ERN1 (0.59) | ALDH1A1ERN1AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL18202850 | 0.74 | NPC1 (0.41) | XDHKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014177517-A1 | PREPARATION PROCESS OF AN AGONIST OF THE THROMBOPOIETIN RECEPTOR | Esteve Química, S.A. (ES) | 2014-11-06 | — | — | WO | disclosed |
| EP-2799425-A1 | Preparation process of an agonist of the thrombopoietin receptor | Esteve Química, S.A. (ES) | 2014-11-05 | — | — | EP | disclosed |