Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 9/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16207603 | 1.00 | PTGER1 (0.60) | PTGER1CYP2C9NR4A2MRGPRX4MEN1 | |
| SCHEMBL16207728 | 0.86 | ALDH1A1 (0.56) | MEN1ALDH1A1KMT2A | |
| SCHEMBL16215971 | 0.83 | PTPN11 (0.55) | MEN1ALDH1A1KMT2ANR1H4 | |
| SCHEMBL1705873 | 0.82 | TPMT (0.50) | ALDH1A1 | |
| SCHEMBL28669741 | 0.81 | ALDH1A1 (0.64) | PTGER1ALDH1A1 | |
| SCHEMBL30008028 | 0.81 | PTGER1 (0.65) | PTGER1CYP2C9NR4A2MRGPRX4MEN1 | |
| SCHEMBL3557707 | 0.78 | MRGPRX4 (0.57) | NR4A2MRGPRX4 | |
| SCHEMBL27388637 | 0.78 | HTR1A (0.55) | MEN1ALDH1A1KMT2A | |
| SCHEMBL3093865 | 0.77 | CTSV (0.58) | PTGER1MEN1ALDH1A1KMT2A | |
| SCHEMBL30542024 | 0.77 | MEN1 (0.50) | PTGER1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119638575-A | Method for preparing key intermediate of eltrombopag by one-pot method | 浙江国邦药业有限公司 | 2025-03-18 | — | — | CN | disclosed |
| CN-116874428-B | PNPO inhibitor with multiple myeloma resisting effect, and preparation method and application thereof | 南京中医药大学 | 2025-01-28 | — | — | CN | disclosed |
| CN-116874428-A | PNPO inhibitor with multiple myeloma resisting effect, and preparation method and application thereof | 南京中医药大学 | 2023-10-13 | — | — | CN | disclosed |
| CN-107021928-B | Eltrombopag intermediate, preparation method and application thereof | 常州制药厂有限公司 | 2022-11-18 | — | — | CN | disclosed |