Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12646998 | 0.85 | PTPN11 (0.46) | PTPN11LMNAHPGDRAB9ANR1H4 | |
| SCHEMBL1638061 | 0.83 | MAOB (0.62) | LMNAHPGDMAOBL3MBTL1PTGER1 | |
| SCHEMBL12765498 | 0.82 | PTPN11 (0.47) | PTPN11LMNANR1H4KDM4EMAPT | |
| SCHEMBL12646896 | 0.80 | CCNE2 (0.47) | PTPN11LMNAKDM4EMAPTTDP1 | |
| SCHEMBL1449798 | 0.80 | MAPT (0.53) | NR1H4MAOBMAPTPTGER1 | |
| SCHEMBL30575453 | 0.78 | PTPN11 (0.49) | PTPN11LMNANR1H4MAPTL3MBTL1 | |
| SCHEMBL11511175 | 0.78 | PTPN11 (0.54) | PTPN11KDM4ETDP1L3MBTL1HDAC8 | |
| SCHEMBL7644233 | 0.77 | PLA2G4B (0.57) | PTPN11NR1H4HDAC8 | |
| SCHEMBL12646856 | 0.77 | PTPN11 (0.43) | PTPN11LMNAKDM4EMAPTTDP1 | |
| SCHEMBL16215971 | 0.76 | PTPN11 (0.55) | PTPN11NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8541522-B2 | Catalyst compounds and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-09-24 | — | — | US | disclosed |
| US-20110098429-A1 | Catalyst Compounds and Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110098429-A1 | Catalyst Compounds and Use Thereof | ALOX12, THEM6, ALOX15 | PTPN11 3000/4885LMNA 4232/4885HPGD 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.