SCHEMBL16218705

SCHEMBL16218705

OBOc1cccc(N(c2ccccc2)c2ccccc2)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP3A4 P08684 2/20 0.36
MAPT P10636 2/20 0.36
CYP2C19 P33261 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
ATM Q13315 2/20 0.35
MTNR1A P48039 5/20 0.33
MTNR1B P49286 5/20 0.33
KMT2A Q03164 2/20 0.32
MEN1 O00255 1/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
TLR9 Q9NR96 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29294352 0.92 MAPT (0.35) L3MBTL1TDP1ALDH1A1CYP3A4MAPT
SCHEMBL18776350 0.92 MAPT (0.35) L3MBTL1TDP1ALDH1A1CYP3A4MAPT
SCHEMBL26815485 0.88 KDM4E (0.33) L3MBTL1TDP1ALDH1A1CYP3A4MAPT
SCHEMBL25921839 0.87 L3MBTL1 (0.38) L3MBTL1TDP1ALDH1A1CYP3A4MAPT
SCHEMBL15553771 0.85 L3MBTL1 (0.39) L3MBTL1TDP1ALDH1A1CYP3A4MAPT
SCHEMBL26815533 0.83 HSD17B1 (0.41) CYP3A4CYP2C19CYP1A2CYP2D6CYP2C9
SCHEMBL14926316 0.82 ALDH1A1 (0.45) L3MBTL1TDP1ALDH1A1CYP3A4MAPT
SCHEMBL8943978 0.78 MAOB (0.48) L3MBTL1TDP1ALDH1A1CYP3A4MAPT
SCHEMBL25982194 0.78 L3MBTL1 (0.41) L3MBTL1TDP1ALDH1A1CYP3A4MAPT
SCHEMBL18119013 0.77 CYP1A2 (0.35) L3MBTL1TDP1ALDH1A1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109810120-B Carbazole-thienopyrazine derivative, preparation method, application and device thereof 武汉尚赛光电科技有限公司 2020-10-30 CN disclosed
US-9905773-B2 Compound for organic electronic element, organic electronic element using the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2018-02-27 US disclosed
US-20140326987-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2014-11-06 US disclosed