SCHEMBL162203

SCHEMBL162203

NC(C(=O)O)c1ccc(F)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.52
TDP1 Q9NUW8 4/20 0.52
MEN1 O00255 3/20 0.52
CYP2C9 P11712 3/20 0.52
KMT2A Q03164 3/20 0.52
CYP2C19 P33261 2/20 0.52
CYP2D6 P10635 1/20 0.52
GRM8 O00222 1/20 0.52
GRM6 O15303 1/20 0.52
SLC6A2 P23975 1/20 0.52
SLC6A4 P31645 1/20 0.52
DRD3 P35462 1/20 0.52
GRM4 Q14833 1/20 0.52
KDM4E B2RXH2 4/20 0.48
ALDH1A1 P00352 4/20 0.48
HPGD P15428 4/20 0.48
GRM1 Q13255 3/20 0.48
GRM2 Q14416 2/20 0.48
HDAC3 O15379 1/20 0.45
HDAC4 P56524 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL205545 1.00 HSD17B10 (0.52) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL207638 1.00 HSD17B10 (0.52) HSD17B10TDP1MEN1CYP2C9KMT2A
Hydrochloric Acid SCHEMBL28010750 0.98 HSD17B10 (0.50) HSD17B10TDP1MEN1CYP2C9KMT2A
Hydrochloric Acid SCHEMBL23112808 0.98 HSD17B10 (0.50) HSD17B10TDP1MEN1CYP2C9KMT2A
Hydrochloric Acid SCHEMBL23112807 0.98 HSD17B10 (0.50) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL30057645 0.94 BCL2L1 (0.50) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL13527786 0.88 HSD17B10 (0.61) HSD17B10TDP1MEN1CYP2C9KMT2A
SCHEMBL6321555 0.82 HDAC3 (0.45) ALDH1A1HDAC3HDAC4HDAC1HDAC7
SCHEMBL10069409 0.82 HDAC3 (0.45) ALDH1A1HDAC3HDAC4HDAC1HDAC7
SCHEMBL5114354 0.82 HDAC3 (0.45) ALDH1A1HDAC3HDAC4HDAC1HDAC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 377 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210032304-A1 FIBROBLAST GROWTH FACTOR ANALOGS AND USES THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2021-02-04 US claimed
EP-3752174-A1 FIBROBLAST GROWTH FACTOR ANALOGS AND USES THEREOF University of Florida Research Foundation, Incorporated (US) 2020-12-23 EP claimed
WO-2019160910-A1 FIBROBLAST GROWTH FACTOR ANALOGS AND USES THEREOF UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) 2019-08-22 WO claimed
US-6949658-B2 Process for producing optically active α-amino acid and optically active α-amino acid amide MITSUBISHI RAYON CO., LTD. (JP) 2005-09-27 US claimed
US-20030171597-A1 Process for producing optically active alpha-amino acid and optically active alpha-amino acid amine MITSUBISHI RAYON CO., LTD. (JP) 2003-09-11 US claimed
EP-1300392-A1 PROCESS FOR PRODUCING OPTICALLY ACTIVE ALPHA-AMINO ACID AND OPTICALLY ACTIVE ALPHA-AMINO ACID AMIDE Mitsubishi Rayon Co., Ltd. (JP) 2003-04-09 EP claimed
EP-0968216-B1 PHOSPHINE LIGANDS WITH AMINO ACID GROUPS, METHOD FOR THEIR PRODUCTION AND USE THEREOF AS CATALYST COMPONENTS CELANESE CHEM EUROPE GMBH (DE) 2002-10-16 EP claimed
US-6300517-B1 SUITABLE AS CONSTITUENTS OF METAL COMPLEXES WHICH CAN BE USED AS CATALYSTS FOR REACTIONS TO FORM C--C, C--H, C--N, C--SI OR C--O BONDS CELANESE GMBH (DE) 2001-10-09 US claimed
US-5658885-A OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) 1997-08-19 US claimed
CN-122081969-A VSe-Cu2-xSe nanosheet catalysis C (sp)3) -H bond CO2Method for directionally synthesizing alpha-hydroxy/amino acid by carboxylation 2026-05-26 CN disclosed
US-20260124204-A1 METALLOENZYME INHIBITOR COMPOUNDS EIKONIZO THERAPEUTICS, INC. (US) 2026-05-07 US disclosed
EP-4127157-B1 MODIFIED DIPEPTIDE CLEAVASES, USES THEREOF AND RELATED KITS ENCODIA INC (US) 2026-02-11 EP disclosed
US-12370194-B2 Metalloenzyme inhibitor compounds EIKONIZO THERAPEUTICS, INC. (US) 2025-07-29 US disclosed
US-12268683-B2 Compounds and methods for synergistic activation of M channels THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-04-08 US disclosed
US-4061851-A 7-Amino-7-arylthio cephalosporins E. R. SQUIBB & SONS, INC. (US) 1977-12-06 US disclosed
US-4061629-A 6-Amino-6-arylthio penicillanic acids and derivatives thereof E. R. SQUIBB & SONS, INC. (US) 1977-12-06 US disclosed
US-4029669-A 6-Benzalimino-6-arylthio penicillanic acids and derivatives thereof E. R. SQUIBB & SONS, INC. (US) 1977-06-14 US disclosed
US-4026886-A 7-Acyl-7-arylthiocephalosporins E. R. SQUIBB & SONS, INC. (US) 1977-05-31 US disclosed
US-3965093-A 6-Arylthio penicillanic acid and derivatives thereof E. R. SQUIBB & SONS, INC. (US) 1976-06-22 US disclosed
US-3954744-A ANTIBACTERIAL E. R. SQUIBB & SONS, INC. (US) 1976-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030171597-A1 Process for producing optically active alpha-amino acid and optically active alpha-amino acid amine AADAT, BCAT1, BCAT2 HSD17B10 1536/4885TDP1 4133/4885MEN1 3310/4885
US-20260124204-A1 METALLOENZYME INHIBITOR COMPOUNDS HDAC6, HDAC3, HDAC1 HSD17B10 211/4885TDP1 2647/4885MEN1 4744/4885
US-12370194-B2 Metalloenzyme inhibitor compounds HDAC6, HDAC1, HDAC2 HSD17B10 448/4885TDP1 1641/4885MEN1 2833/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.