Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT5 | Q96KN8 | 6/20 | 0.50 |
| ▸ | PLAAT4 | Q9UL19 | 6/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 5/20 | 0.50 |
| ▸ | PLAAT2 | Q9NWW9 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1620609 | 0.81 | EGFR (0.49) | PLAAT5PLAAT4PLAAT3PLAAT2LMNA | |
| SCHEMBL7661577 | 0.75 | PLAAT5 (0.63) | PLAAT5PLAAT4PLAAT3PLAAT2LMNA | |
| SCHEMBL12590249 | 0.75 | PLAAT3 (0.47) | PLAAT5PLAAT4PLAAT3PLAAT2LMNA | |
| SCHEMBL17240886 | 0.75 | CACNA1G (0.51) | LMNATP53CACNA1GSMN1; SMN2NPC1 | |
| SCHEMBL6974619 | 0.73 | PLAAT5 (0.65) | PLAAT5PLAAT4PLAAT3PLAAT2LMNA | |
| SCHEMBL7660245 | 0.73 | PLAAT5 (0.68) | PLAAT5PLAAT4PLAAT3PLAAT2LMNA | |
| SCHEMBL7660641 | 0.72 | PLAAT5 (0.58) | PLAAT5PLAAT4PLAAT3PLAAT2LMNA | |
| SCHEMBL6645828 | 0.71 | PLAAT3 (0.57) | PLAAT5PLAAT4PLAAT3PLAAT2LMNA | |
| SCHEMBL6977796 | 0.71 | PLAAT5 (0.70) | PLAAT5PLAAT4PLAAT3PLAAT2LMNA | |
| SCHEMBL7661326 | 0.70 | PLAAT5 (0.65) | PLAAT5PLAAT4PLAAT3PLAAT2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928134-B2 | 5-aryl-4,5-dihydro-(1H)-pyrazolines as cannabinoid CB1 receptor agonists | SOLVAY PHARMACEUTICALS B.V. (NL) | 2011-04-19 | — | — | US | disclosed |
| US-20090082396-A1 | 5-ARYL-4,5-DIHYDRO-(1H)-PYRAZOLINES AS CANNABINOID CB1 RECEPTOR AGONISTS | SOLVAY PHARMACEUTICALS B.V. | 2009-03-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090082396-A1 | 5-ARYL-4,5-DIHYDRO-(1H)-PYRAZOLINES AS CANNABINOID CB1 RECEPTOR AGONISTS | CNR1, CNR2, HTR5A | PLAAT5 514/4885PLAAT4 845/4885PLAAT3 1117/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.