Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 14/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | RAB9A | P51151 | 8/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | GLA | P06280 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 10/20 | 0.96 |
| ▸ | GAA | P10253 | 4/20 | 0.96 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.79 |
| ▸ | NPC1 | O15118 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | THRB | P10828 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | TNF | P01375 | 1/20 | 0.71 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.71 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20248980 | 0.99 | ALDH1A1 (0.98) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL20248969 | 0.98 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL2416525 | 0.89 | MAPK10 (0.82) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL3285611 | 0.88 | MAPK10 (1.00) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL14580981 | 0.87 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL2416715 | 0.86 | ALDH1A1 (0.82) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL15281388 | 0.86 | RAB9A (1.00) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL3279220 | 0.84 | MAPK10 (0.91) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL20248968 | 0.83 | MAPT (1.00) | ALDH1A1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL20248975 | 0.83 | MAPT (0.78) | ALDH1A1MEN1KMT2ARAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10253035-B2 | Eis inhibitors | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2019-04-09 | — | — | US | disclosed |
| EP-2573559-B1 | Modulation of chemosensory receptors and ligands associated therewith | SENOMYX INC (US) | 2019-03-13 | — | — | EP | disclosed |
| US-20180162867-A1 | EIS INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-06-14 | — | — | US | disclosed |
| US-20180162867-A1 | EIS INHIBITORS | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION | 2018-06-14 | — | — | US | disclosed |
| US-9603848-B2 | Modulation of chemosensory receptors and ligands associated therewith | SENOMYX, INC. (US) | 2017-03-28 | — | — | US | disclosed |
| EP-2062050-B1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX INC (US) | 2016-05-18 | — | — | EP | disclosed |
| US-9181276-B2 | Modulation of chemosensory receptors and ligands associated therewith | SENOMYX, INC. (US) | 2015-11-10 | — | — | US | disclosed |
| US-20140235623-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-8633186-B2 | Modulation of chemosensory receptors and ligands associated therewith | SENOMYX INC. (US) | 2014-01-21 | — | — | US | disclosed |
| US-8541421-B2 | Methods of enhancing sweet taste of compositions using substituted thieno{2,3-D}pyrimidines | SENOMYX INC. (US) | 2013-09-24 | — | — | US | disclosed |
| EP-2573559-A1 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-27 | — | — | EP | disclosed |
| EP-2568287-A2 | Modulation of chemosensory receptors and ligands associated | Senomyx, Inc. (US) | 2013-03-13 | — | — | EP | disclosed |
| US-20110230502-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2011-09-22 | — | — | US | disclosed |
| US-20110224155-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX INC. (US) | 2011-09-15 | — | — | US | disclosed |
| US-7928111-B2 | Compounds including substituted thienopyrimidinone derivatives as ligands for modulating chemosensory receptors | SENOMYX, INC. (US) | 2011-04-19 | — | — | US | disclosed |
| EP-2062050-A2 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | Senomyx, Inc. (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008154221-A2 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2008-12-18 | — | — | WO | disclosed |
| US-20080306053-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2008-12-11 | — | — | US | disclosed |
| US-20080306093-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | SENOMYX, INC. (US) | 2008-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230502-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | OR51E2, TAS2R50, TAS2R30 | ALDH1A1 4103/4885MEN1 4289/4885KMT2A 4389/4885 |
| US-20080306093-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | OR51E2, TAS2R50, TAS2R30 | ALDH1A1 4103/4885MEN1 4289/4885KMT2A 4389/4885 |
| US-20140235623-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | TAS2R30, TAS2R50, TAS2R1 | ALDH1A1 4242/4885MEN1 4038/4885KMT2A 4411/4885 |
| US-20080306053-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | OR51E2, TAS2R50, TAS2R30 | ALDH1A1 4103/4885MEN1 4289/4885KMT2A 4389/4885 |
| US-20180162867-A1 | EIS INHIBITORS | EP300, ACAT1, ACAT2 | ALDH1A1 1232/4885MEN1 3656/4885KMT2A 2491/4885 |
| US-10253035-B2 | Eis inhibitors | EP300, ACAT1, ACAT2 | ALDH1A1 1232/4885MEN1 3656/4885KMT2A 2491/4885 |
| US-20110224155-A1 | MODULATION OF CHEMOSENSORY RECEPTORS AND LIGANDS ASSOCIATED THEREWITH | TAS2R30, TAS2R50, TAS2R1 | ALDH1A1 4242/4885MEN1 4038/4885KMT2A 4411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.