Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 14/20 | 0.52 |
| ▸ | MMP3 | P08254 | 13/20 | 0.52 |
| ▸ | MMP8 | P22894 | 4/20 | 0.52 |
| ▸ | MMP2 | P08253 | 14/20 | 0.49 |
| ▸ | MMP7 | P09237 | 4/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16228011 | 1.00 | MMP1 (0.52) | MMP1MMP3MMP8MMP2MMP7 | |
| SCHEMBL14932681 | 0.88 | MMP1 (0.54) | MMP1MMP3MMP8MMP2MMP9 | |
| SCHEMBL14932673 | 0.88 | MMP3 (0.52) | MMP1MMP3MMP8MMP2MMP7 | |
| Hydrochloric Acid SCHEMBL16228017 | 0.87 | MMP3 (0.51) | MMP1MMP3MMP8MMP2MMP7 | |
| Hydrochloric Acid SCHEMBL16228016 | 0.87 | MMP3 (0.51) | MMP1MMP3MMP8MMP2MMP7 | |
| SCHEMBL16288647 | 0.82 | NPY1R (0.49) | — | |
| SCHEMBL11888385 | 0.82 | NPC1 (0.46) | — | |
| SCHEMBL16227576 | 0.82 | NPY4R (0.54) | MMP1MMP3MMP8MMP2 | |
| SCHEMBL8169814 | 0.79 | MMP1 (0.53) | MMP1MMP3MMP8MMP2MMP7 | |
| SCHEMBL8169810 | 0.79 | MMP1 (0.53) | MMP1MMP3MMP8MMP2MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626438-B2 | Fluorescent substrates for determining lysine modifying enzyme activity | THE BROAD INSTITUTE, INC. (US) | 2020-04-21 | — | — | US | disclosed |
| US-20180155760-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | BROAD INST INC (US) | 2018-06-07 | — | — | US | disclosed |
| US-9856509-B2 | Fluorescent substrates for determining lysine modifying enzyme activity | THE BROAD INSTITUTE, INC. (US) | 2018-01-02 | — | — | US | disclosed |
| US-20140335550-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | THE BROAD INSTITUTE, INC. (US) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155760-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | KDM1A, MAN2B1, KDM3A | MMP1 476/4885MMP3 328/4885MMP8 2643/4885 |
| US-10626438-B2 | Fluorescent substrates for determining lysine modifying enzyme activity | KDM1A, MAN2B1, KDM3A | MMP1 476/4885MMP3 328/4885MMP8 2643/4885 |
| US-20140335550-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | MAN2B1, KDM1A, KDM3A | MMP1 481/4885MMP3 328/4885MMP8 2614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.