Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 13/20 | 0.53 |
| ▸ | MMP3 | P08254 | 12/20 | 0.53 |
| ▸ | MMP8 | P22894 | 4/20 | 0.53 |
| ▸ | MMP2 | P08253 | 13/20 | 0.51 |
| ▸ | GNPAT | O15228 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169814 | 1.00 | MMP1 (0.53) | MMP1MMP3MMP8MMP2GNPAT | |
| SCHEMBL8169574 | 0.88 | GNPAT (0.48) | MMP1MMP3MMP8MMP2GNPAT | |
| SCHEMBL14821599 | 0.84 | MMP1 (0.57) | MMP1MMP3MMP8MMP2GNPAT | |
| SCHEMBL23056614 | 0.84 | MMP2 (0.69) | MMP1MMP3MMP8MMP2MMP7 | |
| SCHEMBL24915332 | 0.84 | GNPAT (0.55) | MMP1MMP3MMP8MMP2GNPAT | |
| SCHEMBL22962378 | 0.82 | MMP1 (0.64) | MMP1MMP3MMP8MMP2MMP7 | |
| SCHEMBL19361059 | 0.82 | MMP1 (0.64) | MMP1MMP3MMP8MMP2MMP7 | |
| SCHEMBL12728117 | 0.81 | MMP1 (0.50) | MMP1MMP3MMP8MMP2MMP7 | |
| SCHEMBL29393589 | 0.81 | SIRT5 (0.63) | — | |
| SCHEMBL8174215 | 0.80 | FCER2 (0.48) | MMP1MMP3MMP8MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127341-A | AMINOMETHYL-N-(1-((2-(2-THIENYL)-1-(1-CARBAMOYL-5 -AMINOPENTYLCARBAMOYL)ETHYL)-N-METHYLCARBAMOYL)-2-(2 -NAPTHYL)ETHYL)BENZAMIDE, FOR EXAMPLE; ADMINISTERING TO STIMULATE GROWTH, MILK OR WOOL PRODUCTION IN ANIMALS | NOVO NORDISK A/S (DK) | 2000-10-03 | — | — | US | disclosed |
| EP-1005484-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 2000-06-07 | — | — | EP | disclosed |
| WO-1998058950-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-12-30 | — | — | WO | disclosed |