Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 8/20 | 0.54 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.49 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.49 |
| ▸ | NPY1R | P25929 | 5/20 | 0.49 |
| ▸ | NPY2R | P49146 | 3/20 | 0.49 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP3 | P08254 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.43 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16227501 | 0.94 | NPY4R (0.55) | NPY4RNPBWR1NPY5RNPY1RNPY2R | |
| SCHEMBL14932619 | 0.94 | NPY4R (0.55) | NPY4RNPBWR1NPY5RNPY1RNPY2R | |
| SCHEMBL14932618 | 0.91 | NPY4R (0.51) | NPY4RNPBWR1NPY5RNPY1RNPY2R | |
| SCHEMBL16228013 | 0.82 | MMP1 (0.52) | MMP1MMP3MMP8MMP2 | |
| SCHEMBL16228011 | 0.82 | MMP1 (0.52) | MMP1MMP3MMP8MMP2 | |
| SCHEMBL16234096 | 0.78 | HTRA2 (0.65) | — | |
| SCHEMBL14932681 | 0.75 | MMP1 (0.54) | PSMB5MMP1MMP3MMP8MMP2 | |
| SCHEMBL14932673 | 0.75 | MMP3 (0.52) | MMP1MMP3MMP8MMP2 | |
| SCHEMBL12294934 | 0.74 | PSEN1 (0.51) | NPY4RNPBWR1NPY5RNPY1RNPY2R | |
| Hydrochloric Acid SCHEMBL16228016 | 0.74 | MMP3 (0.51) | MMP1MMP3MMP8MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10626438-B2 | Fluorescent substrates for determining lysine modifying enzyme activity | THE BROAD INSTITUTE, INC. (US) | 2020-04-21 | — | — | US | disclosed |
| US-20180155760-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | BROAD INST INC (US) | 2018-06-07 | — | — | US | disclosed |
| US-9856509-B2 | Fluorescent substrates for determining lysine modifying enzyme activity | THE BROAD INSTITUTE, INC. (US) | 2018-01-02 | — | — | US | disclosed |
| US-20140335550-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | THE BROAD INSTITUTE, INC. (US) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155760-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | KDM1A, MAN2B1, KDM3A | NPY4R 3302/4885NPBWR1 2749/4885NPY5R 2978/4885 |
| US-10626438-B2 | Fluorescent substrates for determining lysine modifying enzyme activity | KDM1A, MAN2B1, KDM3A | NPY4R 3302/4885NPBWR1 2749/4885NPY5R 2978/4885 |
| US-20140335550-A1 | FLUORESCENT SUBSTRATES FOR DETERMINING LYSINE MODIFYING ENZYME ACTIVITY | MAN2B1, KDM1A, KDM3A | NPY4R 3511/4885NPBWR1 2467/4885NPY5R 3462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.