Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SI | P14410 | 1/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8879960 | 0.85 | CSNK2A2 (0.57) | CSNK2A2CSNK2BCSNK2A1MAPTHDAC1 | |
| SCHEMBL161099 | 0.83 | GLS (0.46) | CSNK2A2CSNK2A1MAPTHDAC1HDAC2 | |
| SCHEMBL17978505 | 0.82 | MGAM (0.56) | CSNK2A2CSNK2BCSNK2A1MAPTHDAC1 | |
| SCHEMBL161360 | 0.81 | XDH (0.44) | CSNK2A2CSNK2BCSNK2A1MAPTHDAC1 | |
| SCHEMBL1350599 | 0.78 | MAPT (0.55) | MAPTMEN1KMT2AALDH1A1RAB9A | |
| SCHEMBL159199 | 0.77 | MEN1 (0.52) | MAPTHDAC1HDAC2MEN1KMT2A | |
| SCHEMBL16817718 | 0.76 | CSNK2A2 (0.64) | CSNK2A2CSNK2BCSNK2A1MAPTHDAC1 | |
| SCHEMBL27930311 | 0.75 | CSNK2A2 (0.51) | CSNK2A2CSNK2BCSNK2A1MAPTHDAC1 | |
| SCHEMBL8880665 | 0.75 | MGAM (0.56) | CSNK2A2CSNK2BCSNK2A1MAPTHDAC1 | |
| SCHEMBL162484 | 0.74 | HDAC8 (0.56) | MAPTHDAC1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611783-A2 | HETEROCYCLIC COMPOUNDS AS DGAT1 INHIBITORS | Piramal Enterprises Limited (IN) | 2013-07-10 | — | — | EP | disclosed |
| US-20130158075-A1 | HETEROCYCLIC COMPOUNDS AS DGAT1 INHIBITORS | Piramal Enterprises Limited (IN) | 2013-06-20 | — | — | US | disclosed |
| WO-2012029032-A2 | HETEROCYCLIC COMPOUNDS AS DGAT1 INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130158075-A1 | HETEROCYCLIC COMPOUNDS AS DGAT1 INHIBITORS | DGAT1, DGAT2, SOAT1 | CSNK2A2 2204/4885CSNK2B 2840/4885CSNK2A1 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.