Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 20/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 20/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1108353 | 0.82 | TRPA1 (0.42) | ESR1ESR2HSP90AA1 | |
| SCHEMBL2137945 | 0.75 | ESR1 (0.61) | ESR1ESR2HSP90AA1 | |
| SCHEMBL1101176 | 0.72 | ESR1 (0.45) | ESR1ESR2HSP90AA1 | |
| SCHEMBL8290795 | 0.72 | ESR1 (0.41) | ESR1ESR2HSP90AA1 | |
| SCHEMBL1836503 | 0.72 | ALDH1A1 (0.49) | ESR1ESR2HSP90AA1 | |
| SCHEMBL5512412 | 0.72 | ESR1 (0.42) | ESR1ESR2HSP90AA1 | |
| SCHEMBL14572005 | 0.68 | ALDH1A1 (0.42) | ESR1ESR2HSP90AA1 | |
| SCHEMBL13201416 | 0.68 | TRPA1 (0.47) | ESR1ESR2 | |
| SCHEMBL8291371 | 0.67 | MAOB (0.52) | — | |
| SCHEMBL468359 | 0.66 | ESR1 (0.53) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1988085-B1 | PROCESS FOR PRODUCTION OF 3-[5-[4-(CYCLOPENTYLOXY)-2-HYDROXYBENZOYL]-2-[(3-HYDROXY-1,2-BEZISOXAZOL-6-YL)METHOXY]PHENYL]PROPIONATE ESTER AND INTERMEDIATE FOR THE PROCESS | TOYAMA CHEMICAL CO LTD (JP) | 2014-11-12 | — | — | EP | disclosed |