SCHEMBL16233201

SCHEMBL16233201

Cc1cc(C(=O)NCC2(O)CCCCC2)cc(C)c1OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A5 Q9Y345 3/20 0.59
TAOK1 Q7L7X3 1/20 0.52
TAOK3 Q9H2K8 1/20 0.52
P2RX7 Q99572 14/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
LMNA P02545 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16233223 0.88 SLC6A5 (0.52) SLC6A5TAOK1TAOK3P2RX7LMNA
SCHEMBL16233159 0.87 SLC6A5 (0.78) SLC6A5L3MBTL1LMNAHPGD
SCHEMBL5017438 0.87 SLC6A5 (0.78) SLC6A5TAOK1TAOK3LMNA
SCHEMBL5022176 0.86 SLC6A5 (0.77) SLC6A5TAOK1TAOK3LMNA
SCHEMBL5017330 0.83 SLC6A5 (0.74) SLC6A5TAOK1TAOK3LMNA
SCHEMBL16233224 0.82 HCN1 (0.61) SLC6A5LMNA
SCHEMBL16233240 0.81 PARP10 (0.53) SLC6A5LMNA
SCHEMBL13293412 0.80 BRD4 (0.56) SLC6A5TAOK1TAOK3L3MBTL1LMNA
SCHEMBL6013403 0.79 SLC6A5 (0.89) SLC6A5TAOK1TAOK3L3MBTL1LMNA
SCHEMBL16233249 0.79 SLC6A5 (0.64) SLC6A5TAOK1TAOK3LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9359346-B2 Benzamide derivative and use thereof VIVOZON, INC. (KR) 2016-06-07 US disclosed
US-9359346-B2 Benzamide derivative and use thereof VIVOZON, INC. (KR) 2016-06-07 US disclosed
US-20140336378-A1 NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF VIVOZON, INC. (KR) 2014-11-13 US disclosed
US-20140336378-A1 NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF VIVOZON, INC. (KR) 2014-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140336378-A1 NOVEL BENZAMIDE DERIVATIVE AND USE THEREOF TRPV1, TRPA1, TRPV5 SLC6A5 1714/4885TAOK1 3998/4885TAOK3 3622/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.