Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | FLT4 | P35916 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235383 | 0.84 | HTT (0.33) | — | |
| SCHEMBL16235114 | 0.82 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL16235054 | 0.81 | HTT (0.31) | MAPT | |
| SCHEMBL16235234 | 0.80 | FLT1 (0.38) | ALDH1A1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL16235789 | 0.74 | ALDH1A1 (0.33) | ALDH1A1MAPT | |
| SCHEMBL16235389 | 0.72 | HTT (0.30) | — | |
| SCHEMBL30602411 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL29130946 | 0.72 | ALDH1A1 (0.36) | ALDH1A1MAPTRXFP1MEN1KMT2A | |
| SCHEMBL16235182 | 0.71 | AR (0.34) | ALDH1A1MAPT | |
| SCHEMBL16235562 | 0.71 | MEN1 (0.34) | ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925743-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | Active Biotech AB (SE) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014184234-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2014-11-20 | — | — | WO | disclosed |