Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16234926 | 0.91 | TRPV4 (0.32) | ALDH1A1LMNAHTTMAPTL3MBTL1 | |
| SCHEMBL16235303 | 0.82 | HTT (0.32) | ARHTT | |
| SCHEMBL16235234 | 0.80 | FLT1 (0.38) | ALDH1A1HTTMAPTL3MBTL1 | |
| SCHEMBL16235389 | 0.78 | HTT (0.30) | HTT | |
| SCHEMBL16234950 | 0.74 | HTT (0.33) | ALDH1A1HTTMAPT | |
| SCHEMBL16235789 | 0.72 | ALDH1A1 (0.33) | ALDH1A1LMNAHTTMAPT | |
| SCHEMBL16235179 | 0.71 | S100A9 (0.49) | AR | |
| SCHEMBL16235185 | 0.71 | LMNA (0.42) | ARALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL16235458 | 0.68 | ATF1 (0.35) | LMNAHTTHPGDL3MBTL1 | |
| SCHEMBL19493136 | 0.67 | AR (0.48) | ARTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925743-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | Active Biotech AB (SE) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014184234-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2014-11-20 | — | — | WO | disclosed |