Sugi Predict

Sugi Predict / Compounds / SCHEMBL16235054

SCHEMBL16235054

SCHEMBL16235054

CCSc1cc(OC)c(N(c2cc(Cl)cc(Cl)c2)S(C)(=O)=O)nn1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ HTT P42858 1/20 0.31
▸ L3MBTL1 Q9Y468 1/20 0.30
▸ TRPV4 Q9HBA0 1/20 0.30
▸ TP53 P04637 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16235789 0.86 ALDH1A1 (0.33) HTTMAPT
SCHEMBL16234970 0.81 ALDH1A1 (0.31) MAPT
SCHEMBL16235383 0.75 HTT (0.33) HTT
SCHEMBL16235182 0.74 AR (0.34) HTTL3MBTL1MAPT
SCHEMBL16235234 0.73 FLT1 (0.38) HTTL3MBTL1MAPTSMN1; SMN2
SCHEMBL16235389 0.71 HTT (0.30) HTTTRPV4
SCHEMBL30602330 0.69 PGK1 (0.35) HTTL3MBTL1MAPTSMN1; SMN2
SCHEMBL29130907 0.69 PGK1 (0.35) HTTL3MBTL1MAPTSMN1; SMN2
SCHEMBL16235303 0.69 HTT (0.32) HTT
SCHEMBL16235287 0.69 RAB9A (0.38) HTTL3MBTL1TP53SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2925743-A1 N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS Active Biotech AB (SE) 2015-10-07 — — EP disclosed
WO-2014184234-A1 N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS ACTIVE BIOTECH AB (SE) 2014-11-20 — — WO disclosed
Send feedback