Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235139 | 0.85 | CCR4 (0.39) | CCR4ALDH1A1EDNRAMEN1KMT2A | |
| SCHEMBL16235348 | 0.78 | CCR4 (0.35) | CCR4 | |
| SCHEMBL16235146 | 0.72 | CCR4 (0.48) | CCR4 | |
| SCHEMBL16235266 | 0.72 | MAPT (0.38) | ALDH1A1PDE4BMEN1KMT2AUSP2 | |
| SCHEMBL16234926 | 0.70 | TRPV4 (0.32) | ALDH1A1LMNAMAPT | |
| SCHEMBL16235054 | 0.68 | HTT (0.31) | MAPT | |
| SCHEMBL16235182 | 0.64 | AR (0.34) | ALDH1A1LMNAMAPT | |
| SCHEMBL3807134 | 0.63 | PIK3CA (0.50) | ALDH1A1MEN1KMT2ALMNAMAPT | |
| SCHEMBL16235234 | 0.62 | FLT1 (0.38) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL16235389 | 0.60 | HTT (0.30) | CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925743-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | Active Biotech AB (SE) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014184234-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2014-11-20 | — | — | WO | disclosed |