Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235791 | 0.83 | CCR4 (0.43) | CCR4 | |
| SCHEMBL16235148 | 0.78 | CCR4 (0.38) | CCR4 | |
| SCHEMBL16235389 | 0.72 | HTT (0.30) | CCR4 | |
| SCHEMBL16235139 | 0.70 | CCR4 (0.39) | CCR4 | |
| SCHEMBL16235505 | 0.70 | CCR4 (0.70) | CCR4 | |
| SCHEMBL16235303 | 0.70 | HTT (0.32) | — | |
| SCHEMBL16235234 | 0.69 | FLT1 (0.38) | — | |
| SCHEMBL16235648 | 0.69 | S100A9 (0.33) | — | |
| SCHEMBL16235741 | 0.69 | CCR4 (0.33) | CCR4 | |
| SCHEMBL16235182 | 0.68 | AR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925743-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | Active Biotech AB (SE) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014184234-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2014-11-20 | — | — | WO | disclosed |