Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235182 | 0.82 | AR (0.34) | HTTAR | |
| SCHEMBL16234950 | 0.81 | HTT (0.33) | HTTTSHR | |
| SCHEMBL16235389 | 0.80 | HTT (0.30) | HTT | |
| SCHEMBL16235234 | 0.77 | FLT1 (0.38) | HTT | |
| SCHEMBL16235383 | 0.72 | HTT (0.33) | HTT | |
| SCHEMBL16235348 | 0.70 | CCR4 (0.35) | — | |
| SCHEMBL16235458 | 0.69 | ATF1 (0.35) | HTT | |
| SCHEMBL16235054 | 0.69 | HTT (0.31) | HTT | |
| SCHEMBL16234970 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL16235260 | 0.66 | S100A9 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2925743-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | Active Biotech AB (SE) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014184234-A1 | N-(HETEROARYL)-SULFONAMIDE DERIVATIVES USEFUL AS S100-INHIBITORS | ACTIVE BIOTECH AB (SE) | 2014-11-20 | — | — | WO | disclosed |