SCHEMBL16236142

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16239185	0.89	ALDH1A1 (0.47)	ALDH1A1HSD17B10HPGDKDM4ETP53
	SCHEMBL16235879	0.89	ALDH1A1 (0.64)	ALDH1A1HSD17B10HPGDKDM4ETP53
	SCHEMBL16235702	0.82	LMNA (0.43)	ALDH1A1HSD17B10HPGDKDM4ETP53
	SCHEMBL16236256	0.82	HSD17B10 (0.49)	ALDH1A1HSD17B10HPGDKDM4ETP53
	SCHEMBL17628542	0.79	POLB (0.53)	ALDH1A1HSD17B10HPGDKDM4ETP53
	SCHEMBL16235753	0.78	ALDH1A1 (0.53)	ALDH1A1HSD17B10HPGDKDM4EHTT
	SCHEMBL16235966	0.78	NPC1 (0.43)	ALDH1A1HSD17B10HPGDKDM4ETP53
	SCHEMBL16236033	0.77	HSD17B10 (0.52)	ALDH1A1HSD17B10HPGDTSHRMEN1
	SCHEMBL16239303	0.76	TYMS (0.41)	ALDH1A1HSD17B10HPGDKDM4ETP53
	SCHEMBL18113265	0.74	TSHR (0.59)	ALDH1A1HSD17B10HPGDKDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.