Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16236033 | 0.86 | HSD17B10 (0.52) | HSD17B10ALDH1A1HPGDTSHRNPC1 | |
| SCHEMBL16239303 | 0.85 | TYMS (0.41) | HSD17B10ALDH1A1HPGDTYMSKDM4E | |
| SCHEMBL16236142 | 0.82 | ALDH1A1 (0.53) | HSD17B10ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL16239219 | 0.82 | HSD17B10 (0.48) | HSD17B10ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL16235879 | 0.81 | ALDH1A1 (0.64) | HSD17B10ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL16235702 | 0.81 | LMNA (0.43) | HSD17B10ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL16236443 | 0.81 | NPC1 (0.40) | HSD17B10ALDH1A1HPGDTYMSKDM4E | |
| SCHEMBL16235755 | 0.80 | ALDH1A1 (0.46) | HSD17B10ALDH1A1HPGDTSHRKDM4E | |
| SCHEMBL1958548 | 0.80 | TYMS (0.49) | HSD17B10ALDH1A1HPGDTYMSTSHR | |
| SCHEMBL16236375 | 0.78 | ALDH1A1 (0.45) | HSD17B10ALDH1A1HPGDTSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10005860-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2018-06-26 | — | — | US | disclosed |
| EP-2997049-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2017-08-23 | — | — | EP | disclosed |
| US-20170166667-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2017-06-15 | — | — | US | disclosed |
| US-9644051-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2017-05-09 | — | — | US | disclosed |
| US-20160090428-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia, s.r.l. (IT) | 2016-03-31 | — | — | US | disclosed |
| EP-2997049-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184289-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-11-20 | — | — | WO | disclosed |
| EP-2803679-A1 | Catalyst components for the polymerization of olefins | Basell Poliolefine Italia S.r.l. (IT) | 2014-11-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10005860-B2 | Catalyst components for the polymerization of olefins | OXER1, OXSR1, NR0B2 | HSD17B10 1221/4885ALDH1A1 2092/4885HPGD 2211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.