SCHEMBL16236394

SCHEMBL16236394

CC1(C(=O)O)CSC(CC2CC2)=N1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GABRA5 P31644 1/20 0.34
GABRB2 P47870 1/20 0.34
KCNH2 Q12809 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
RECQL P46063 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16236396 1.00 GABRA5 (0.34) GABRA5GABRB2KCNH2HRH3MEN1
SCHEMBL5711263 0.70 GABRA5 (0.37) GABRA5GABRB2
SCHEMBL6835640 0.70 GABRA5 (0.37) GABRA5GABRB2
SCHEMBL5711305 0.68 GABRA5 (0.56) GABRA5GABRB2ALDH1A1
SCHEMBL6315318 0.62 THRB (0.34) GABRA5GABRB2ALDH1A1
SCHEMBL5914861 0.62 THRB (0.34) GABRA5GABRB2ALDH1A1
Deferitrin SCHEMBL18103545 0.58 TYR (0.35) ALDH1A1GAA
SCHEMBL16236392 0.57 KMT2A (0.32) KMT2A
SCHEMBL5377567 0.56
SCHEMBL5428847 0.52 MAPK1 (0.42) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014185853-A1 COMPOUNDS AND METHODS FOR TREATMENT OF CHLAMYDIA INFECTIONS QURETECH BIO AB (SE) 2014-11-20 WO disclosed