Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | GNPAT | O15228 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22592147 | 0.82 | KDM4E (0.42) | ALOX15BLMKDM4EMAPTTHRB | |
| SCHEMBL28243836 | 0.81 | MAPT (0.61) | ALOX15BLMKDM4EMAPTTHRB | |
| SCHEMBL468816 | 0.81 | KDM4E (0.45) | ALOX15BLMKDM4EMAPTTHRB | |
| SCHEMBL1576871 | 0.81 | KDM4E (0.45) | ALOX15BLMKDM4EMAPTTHRB | |
| SCHEMBL8134268 | 0.81 | KDM4E (0.45) | ALOX15BLMKDM4EMAPTTHRB | |
| SCHEMBL27410307 | 0.81 | KDM4E (0.45) | ALOX15BLMKDM4EMAPTTHRB | |
| SCHEMBL468815 | 0.81 | KDM4E (0.45) | ALOX15BLMKDM4EMAPTTHRB | |
| SCHEMBL13953561 | 0.81 | KDM4E (0.45) | ALOX15BLMKDM4EMAPTTHRB | |
| SCHEMBL11134229 | 0.81 | MAPT (0.61) | ALOX15BLMKDM4EMAPTTHRB | |
| SCHEMBL20951073 | 0.80 | ALDH1A1 (0.53) | ALDH1A1SIRT5GNPATCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190142941-A1 | BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same | ABBVIE INC (US) | 2019-05-16 | — | — | US | disclosed |
| US-20150328283-A1 | NOVEL ANTIMICROBIAL AGENTS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2015-11-19 | — | — | US | disclosed |
| WO-2014184584-A1 | DELIVERY PEPTIDES | KING'S COLLEGE LONDON (GB) | 2014-11-20 | — | — | WO | disclosed |
| US-20110136726-A1 | NOVEL ANTIMICROBIAL AGENTS | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136726-A1 | NOVEL ANTIMICROBIAL AGENTS | NOTUM, DAO, SLC11A2 | ALOX15 584/4885BLM 3997/4885KDM4E 4611/4885 |
| US-20150328283-A1 | NOVEL ANTIMICROBIAL AGENTS | ALOX15B, ALOX15, ALOX12 | ALOX15 2/4885BLM 4019/4885KDM4E 4649/4885 |
| US-20190142941-A1 | BCL-XL Inhibitory Compounds Having Low Cell Permeability and Antibody Drug Conjugates Including the Same | BCL2, BAX, BCL9 | ALOX15 3591/4885BLM 2239/4885KDM4E 1299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.