SCHEMBL16238985

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1138972	0.87	MEN1 (0.57)	MEN1ALDH1A1KMT2AKDM4EGAA
	SCHEMBL2567685	0.81	NR1H3 (0.71)	MEN1ALDH1A1KMT2AMAPTFFAR4
	SCHEMBL31301150	0.81	KEAP1 (0.55)	MEN1ALDH1A1KMT2AFFAR4PGR
	SCHEMBL16238966	0.81	KEAP1 (0.55)	MEN1ALDH1A1KMT2AFFAR4PGR
	SCHEMBL16239045	0.81	KEAP1 (0.55)	MEN1ALDH1A1KMT2AGAAMAPT
	SCHEMBL11390047	0.79	ALDH1A1 (0.81)	MEN1ALDH1A1KMT2AKDM4EGAA
	SCHEMBL15646797	0.78	KMT2A (0.58)	MEN1ALDH1A1KMT2AKDM4EGAA
	SCHEMBL6657103	0.77	GAA (0.72)	MEN1ALDH1A1KMT2AKDM4EGAA
	SCHEMBL6976724	0.75	PPARG (0.57)	MAPTFFAR4NR1H3ARNR3C1
	Hydrochloric Acid SCHEMBL10529934	0.75	ALDH1A1 (0.73)	MEN1ALDH1A1KMT2AKDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.