SCHEMBL162390

SCHEMBL162390

CC(=O)OC(=O)c1ccccc1O.[SrH2]

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.62
TSHR P16473 2/20 0.62
HPGD P15428 7/20 0.53
HSD17B10 Q99714 4/20 0.53
ALOX15 P16050 2/20 0.53
TDP1 Q9NUW8 2/20 0.52
ALDH1A1 P00352 6/20 0.49
KDM4E B2RXH2 5/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
HMGB1 P09429 1/20 0.48
CA4 P22748 1/20 0.48
CA6 P23280 1/20 0.48
CA7 P43166 1/20 0.48
CA9 Q16790 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
CA14 Q9ULX7 1/20 0.48
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL285141 0.98 LMNA (0.64) LMNATSHRHPGDHSD17B10ALOX15
Hydrochloric Acid SCHEMBL11262444 0.96 LMNA (0.62) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL9636052 0.96 LMNA (0.62) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL13570450 0.96 TSHR (0.62) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL7761655 0.96 LMNA (0.62) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL11337153 0.96 LMNA (0.62) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL7761593 0.96 LMNA (0.62) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL6245920 0.96 LMNA (0.62) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL9636042 0.96 LMNA (0.62) LMNATSHRHPGDHSD17B10ALOX15
SCHEMBL28461971 0.96 LMNA (0.62) LMNATSHRHPGDHSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170189443-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS PLATINUM MONTAUR LIFE SCIENCES, LLC AND AS AGENT (KY) 2017-07-06 US claimed
EP-3110427-A1 COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE Urigen Pharmaceuticals, Inc. (US) 2017-01-04 EP claimed
WO-2015127416-A1 COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE URIGEN PHARMACEUTICALS, INC. (US) 2015-08-27 WO claimed
US-20090035315-A1 Method of Improving Treatments in Rheumatic and Arthritic Diseases OSTEOLOGIX A/S (DK) 2009-02-05 US claimed
US-20080317849-A1 Method for Improving the Medical Treatment of Pain OSTEOLOGIX A/S (DK) 2008-12-25 US claimed
WO-2007149815-A1 STRONTIUM COMPOSITIONS AND METHODS OF TREATING ARTHRITIC AND OR OSTEOPORITIC CONDITIONS THERAGENEX, LLC (US) 2007-12-27 WO claimed
WO-2007149816-A2 STRONTIUM COMPOSITIONS AND METHODS OF TREATING OSTEOPOROTIC CONDITIONS THERAGENEX, LLC (US) 2007-12-27 WO claimed
US-20070292535-A1 Strontium compositions and methods of treating arthritic and or osteoporitic conditions TRX PHARMACEUTICALS, LLC 2007-12-20 US claimed
US-20070292529-A1 Strontium compositions and methods of treating osteoporotic conditions TRX PHARMACEUTICALS, LLC 2007-12-20 US claimed
EP-1758652-A2 IMPROVING PAIN TREATMENT WITH STRONTIUM COMBINATIONS Osteologix A/S (DK) 2007-03-07 EP claimed
EP-1758653-A2 TREATMENTS COMPRISING STRONTIUM FOR RHEUMATIC AND ARTHRITIC DISEASES AND PAIN Osteologix A/S (DK) 2007-03-07 EP claimed
WO-2005123098-A2 PREVENTING GASTROINTESTINAL SIDE-EFFECTS WITH STRONTIUM SALTS OSTEOLOGIX A/S (DK) 2005-12-29 WO claimed
WO-2005123192-A2 IMPROVING PAIN TREATMENT WITH STRONTIUM COMBINATIONS OSTEOLOGIX A/S (DK) 2005-12-29 WO claimed
WO-2005123130-A2 IMPROVED TREATMENTS OF RHEUMATIC AND ARTHRITIC DISEASES COMPRISING COMBINATIONS OF A 5-LIPOXYGENASE INHIBITOR OSTEOLOGIX A/S (DK) 2005-12-29 WO claimed
WO-2005123193-A2 TREATMENTS COMPRISING STRONTIUM FOR RHEUMATIC AND ARTHRITIC DISEASES AND PAIN OSTEOLOGIX A/S (DK) 2005-12-29 WO claimed
US-20240060997-A1 Blood Preparation and Profiling SANGUI BIO PTY LTD (AU) 2024-02-22 US disclosed
US-11693006-B2 Blood profiling with protease inhibitors SANGUI BIO PTY. LTD (AU) 2023-07-04 US disclosed
EP-1758653-A2 TREATMENTS COMPRISING STRONTIUM FOR RHEUMATIC AND ARTHRITIC DISEASES AND PAIN Osteologix A/S (DK) 2007-03-07 EP disclosed
WO-2005123130-A2 IMPROVED TREATMENTS OF RHEUMATIC AND ARTHRITIC DISEASES COMPRISING COMBINATIONS OF A 5-LIPOXYGENASE INHIBITOR OSTEOLOGIX A/S (DK) 2005-12-29 WO disclosed
WO-2005123193-A2 TREATMENTS COMPRISING STRONTIUM FOR RHEUMATIC AND ARTHRITIC DISEASES AND PAIN OSTEOLOGIX A/S (DK) 2005-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170189443-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS SI, SLC20A1, SLC20A2 LMNA 4376/4885TSHR 4340/4885HPGD 1489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.