Questiomycin B

Questiomycin B

SCHEMBL16239659

CN(C)Cc1ccccc1O.Nc1ccccc1O

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 13/20 0.57
SLC6A2 P23975 11/20 0.57
SLC6A3 Q01959 7/20 0.57
ALOX15 P16050 1/20 0.56
TSHR P16473 1/20 0.56
TDP1 Q9NUW8 2/20 0.45
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
POLB P06746 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
THRB P10828 1/20 0.45
G6PD P11413 1/20 0.45
PABPC1 P11940 1/20 0.45
KMT2A Q03164 1/20 0.45
HKDC1 Q2TB90 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
HSPA5 P11021 1/20 0.43
HTR2A P28223 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL116610 0.88 ALDH1A1 (0.56) SLC6A4SLC6A2ALOX15TSHRTDP1
SCHEMBL29354255 0.88 ALDH1A1 (0.56) SLC6A4SLC6A2ALOX15TSHRTDP1
Hydrochloric Acid SCHEMBL6915484 0.86 ALDH1A1 (0.54) SLC6A4SLC6A2ALOX15TSHRTDP1
SCHEMBL28611072 0.86 ALDH1A1 (0.54) SLC6A4SLC6A2ALOX15TSHRTDP1
Hydrochloric Acid SCHEMBL27583168 0.86 ALDH1A1 (0.54) SLC6A4SLC6A2ALOX15TSHRTDP1
Boric Acid SCHEMBL4657394 0.82 KDM4E (0.50) SLC6A4SLC6A2ALOX15TSHRTDP1
Monoethanolamine SCHEMBL11317599 0.81 TAAR1 (0.52) SLC6A4SLC6A2SLC6A3ALOX15TSHR
SCHEMBL6833269 0.81 KDM4E (0.45) SLC6A4SLC6A2SLC6A3ALOX15TSHR
SCHEMBL4313605 0.80 SLC6A4 (0.63) SLC6A4SLC6A2SLC6A3TSHRTDP1
Questiomycin B SCHEMBL27708789 0.80 ALOX15 (0.79) SLC6A4SLC6A2SLC6A3ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2588554-B1 STORAGE-STABLE HEAT-ACTIVATED TERTIARY AMINE CATALYSTS FOR EPOXY RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-19 EP claimed