SCHEMBL4313605

SCHEMBL4313605

CN(C)Cc1ccccc1N

nearest known ligand 0.63

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 16/20 0.63
SLC6A2 P23975 11/20 0.63
SLC6A3 Q01959 7/20 0.63
TDP1 Q9NUW8 1/20 0.49
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1257763 0.82 SLC6A4 (0.55) SLC6A4SLC6A2SLC6A3TDP1
SCHEMBL125255 0.82 ALDH1A1 (0.57) SLC6A4SLC6A2SLC6A3ALDH1A1TSHR
SCHEMBL29729780 0.82 ALDH1A1 (0.57) SLC6A4SLC6A2SLC6A3ALDH1A1TSHR
SCHEMBL5913443 0.80 SLC6A4 (0.53) SLC6A4SLC6A2SLC6A3TDP1ALDH1A1
SCHEMBL32667982 0.80 ALOX15 (0.45) SLC6A4SLC6A2SLC6A3TDP1ALDH1A1
Questiomycin B SCHEMBL16239659 0.80 SLC6A4 (0.57) SLC6A4SLC6A2SLC6A3TDP1ALDH1A1
SCHEMBL20467041 0.79 SLC6A4 (0.43) SLC6A4SLC6A2SLC6A3TDP1
SCHEMBL248661 0.79 SLC6A4 (0.51) SLC6A4SLC6A2SLC6A3TDP1
SCHEMBL28498759 0.79 HDAC3 (0.46) SLC6A4SLC6A2SLC6A3ALDH1A1
SCHEMBL8533846 0.78 SLC6A4 (1.00) SLC6A4SLC6A2SLC6A3TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120184645-A1 RESINOUS DISPERSIONS INCLUDING AN EPOXY AMINE ADDUCT FOR FLATTING AND RELATED ELECTRODEPOSITABLE COATING COMPOSITIONS PPG INDUSTRIES OHIO, INC. (US) 2012-07-19 US claimed
US-12310944-B2 Selective butyrylcholinesterase inhibitor or pharmaceutically acceptable salt thereof, preparation method and use thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2025-05-27 US disclosed
US-20230165833-A1 Selective Butyrylcholinesterase Inhibitor or Pharmaceutically Acceptable Salt Thereof, Preparation Method and Use Thereof CHINA PHARMACEUTICAL UNIVERSITY (CN) 2023-06-01 US disclosed
US-20210380592-A1 COMPOUND HAVING BENZO SEVEN-MEMBERED RING STRUCTURE, PREPARATION METHOD THEREFOR, AND USE THEREOF BIONNA (BEIJING) MEDICAL TECHNOLOGY CO., LTD. (CN) 2021-12-09 US disclosed
EP-3919479-A1 COMPOUND HAVING BENZO SEVEN-MEMBERED RING STRUCTURE, PREPARATION METHOD THEREFOR, AND USE THEREOF Bionna (Beijing) Medical Technology Co., Ltd. (CN) 2021-12-08 EP disclosed
WO-2021042410-A1 SELECTIVE BUTYRYLCHOLINESTERASE INHIBITOR OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 中国药科大学 2021-03-11 WO disclosed
EP-3696174-A1 HETEROCYCLIC MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS Vertex Pharmaceuticals Incorporated (US) 2020-08-19 EP disclosed
WO-2020156357-A1 COMPOUND HAVING BENZO SEVEN-MEMBERED RING STRUCTURE, PREPARATION METHOD THEREFOR, AND USE THEREOF 博诺康源(北京)药业科技有限公司 2020-08-06 WO disclosed
EP-3152202-B1 3,5-DICHLORO,4-(3,4-(CYCLO-)ALKOXYPHENYL)--2-CARBONYLOXY)ETHYL)PYRIDINE DERIVATIVES AS PDE-4 INHIBITORS AND MUSCARINIC M3 RECEPTOR ANTAGONISTS CHIESI FARM SPA (IT) 2018-11-28 EP disclosed
US-10087176-B2 3,5-dichloro,4-(3,4-(cyclo-)alkoxyphenyl)--2-carbonyloxy)ethyl)pyridine derivatives as PDE-4 inhibitors CHIESI FARMACEUTICI S.P.A. (IT) 2018-10-02 US disclosed
US-5852030-A Indole derivatives, process for producing the same and medicinal uses of the same TORAY INDUSTRIES, INC. (JP) 1998-12-22 US disclosed
WO-1998038378-A1 CARBAMATE MODIFIED LOW-MOLECULAR POLYMER COMPOUND AND THE USE THEREOF FOR AFTER-TREATMENT OF DYED OR PRINTED CELLULOSE TEXTILE MATERIAL TEXTILCOLOR AG (CH) 1998-09-03 WO disclosed
EP-0492501-B1 Surface-active triazine compounds, process for their preparation and their use HOECHST AG (DE) 1996-11-20 EP disclosed
EP-0614898-A1 INDOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 1994-09-14 EP disclosed
US-5240499-A Polymeric pigments HOECHST AKTIENGESELLSCHAFT (DE) 1993-08-31 US disclosed
EP-0492501-A1 Surface-active triazine compounds, process for their preparation and their use HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-01 EP disclosed
US-4676803-A Reactive azo dyestuffs, free from anionic groups and containing a basic group and halogenotriazinyl radical and useful for dyeing cellulose/polyester BAYER AKTIENGESELLSCHAFT (DE) 1987-06-30 US disclosed
EP-0022209-B1 FLUOR-TRIAZINE DYESTUFFS AND THEIR USE IN DYEING CELLULOSIC FIBROUS MATERIALS BAYER AG (DE) 1985-04-17 EP disclosed
US-4503224-A FIBER-REACTIVE, COTTON-POLYESTER BLENDS BAYER AKTIENGESELLSCHAFT (DE) 1985-03-05 US disclosed
EP-0022209-A2 Fluor-triazine dyestuffs and their use in dyeing cellulosic fibrous materials BAYER AG (DE) 1981-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165833-A1 Selective Butyrylcholinesterase Inhibitor or Pharmaceutically Acceptable Salt Thereof, Preparation Method and Use Thereof BCHE, ACHE, BACE1 SLC6A4 86/4885SLC6A2 9/4885SLC6A3 60/4885
US-20210380592-A1 COMPOUND HAVING BENZO SEVEN-MEMBERED RING STRUCTURE, PREPARATION METHOD THEREFOR, AND USE THEREOF BRD4, BRD7, BICRA SLC6A4 3089/4885SLC6A2 4173/4885SLC6A3 3586/4885
US-10087176-B2 3,5-dichloro,4-(3,4-(cyclo-)alkoxyphenyl)--2-carbonyloxy)ethyl)pyridine derivatives as PDE-4 inhibitors PDE4A, PDE4B, PDE4D SLC6A4 1865/4885SLC6A2 3271/4885SLC6A3 1230/4885
US-12310944-B2 Selective butyrylcholinesterase inhibitor or pharmaceutically acceptable salt thereof, preparation method and use thereof BCHE, ACHE, BACE1 SLC6A4 93/4885SLC6A2 8/4885SLC6A3 53/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.